Azaspiracid: First evidence of protein binding in shellfish

The occurrence of azaspiracid (AZA) toxins in contaminated shellfish has been the focus of much research. The present study investigated the binding properties of these toxins in mussels of the species Mytilus edulis. The work involved extraction of proteins and AZAs from contaminated mussel hepatop...

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Veröffentlicht in:	Toxicon (Oxford) 2008-06, Vol.51 (7), p.1255-1263
Hauptverfasser:	Nzoughet, K.J., Hamilton, J.T.G., Floyd, S.D., Douglas, A., Nelson, J., Devine, L., Elliott, C.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal poisons toxicology. Antivenoms Animals Azaspiracids (AZAs) Biological and medical sciences Biomarkers - chemistry Chromatography, High Pressure Liquid Electrophoresis, Polyacrylamide Gel Environmental Monitoring Food Contamination - analysis Foodborne Diseases Hepatopancreas - chemistry Hepatopancreas - metabolism Isoelectric Focusing Isoelectric focusing (IEF) Liquid chromatography coupled with tandem mass spectrometry analysis (LC–MS/MS) Marine Marine Toxins - analysis Marine Toxins - metabolism Medical sciences Mytilus edulis Mytilus edulis - chemistry Protein Protein Binding Proteins - chemistry Proteins - metabolism Shellfish Size exclusion chromatography (SEC) Sodium docecyl sulphate–polyacrylamide gel electrophoresis (SDS–PAGE) Spiro Compounds - analysis Spiro Compounds - metabolism Tandem Mass Spectrometry Toxicology
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