Comparison of free-radical inhibiting antioxidant properties of carvedilol and its phenolic metabolites

Carvedilol is a widely prescribed drug for the treatment of heart failure and the prevention of associated ventricular arrhythmias. It has also been reported to function as a biological antioxidant hydrogen atom transfer from its carbazole N-H moiety to chain-propagating radicals. Metabolites of the...

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Veröffentlicht in:MedChemComm 2017-03, Vol.8 (3), p.606-615
Hauptverfasser: Malig, Thomas C, Ashkin, Mitchell R, Burman, Austin L, Barday, Manuel, Heyne, Belinda J M, Back, Thomas G
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Sprache:eng
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