FKBP5 polymorphisms and hypothalamic-pituitary-adrenal axis negative feedback in major depression and obsessive-compulsive disorder

Major depressive disorder (MDD) and obsessive-compulsive disorder (OCD) have both been linked to abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. Polymorphisms in the genes involved in HPA axis activity, such as FKBP5, and their interactions with childhood trauma have been associated...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of psychiatric research 2018-09, Vol.104, p.227-234
Hauptverfasser:	Ferrer, Alex, Costas, Javier, Labad, Javier, Salvat-Pujol, Neus, Segalàs, Cinto, Urretavizcaya, Mikel, Real, Eva, de Arriba-Arnau, Aida, Alonso, Pino, Crespo, José M., Barrachina, Marta, Soriano-Mas, Carles, Carracedo, Ángel, Menchón, José M., Soria, Virginia
Format:	Artikel
Sprache:	eng
Schlagworte:	Cortisol Dexamethasone suppression test FKBP5 HPA axis Major depression OCD Trait anxiety
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!