Interleukin 13 Increases Contractility of Murine Tracheal Smooth Muscle by a Phosphoinositide 3-kinase p110δ-Dependent Mechanism

The Th2 cytokine interleukin (IL) 13 can elicit a number of responses consistent with a key role in the pathogenesis of asthma. We have used pharmacological and genetic approaches to demonstrate the role of signaling via the class I phosphoinositide 3-kinase p110 delta isoform in IL-13-induced hyper...

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Veröffentlicht in:	Molecular pharmacology 2008-05, Vol.73 (5), p.1530-1537
Hauptverfasser:	Farghaly, Hanan S. M., Blagbrough, Ian S., Medina-Tato, David A., Watson, Malcolm L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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