Long-Term Health Outcome and Quality of Life Post-HSCT for IL7Rα-, Artemis-, RAG1- and RAG2-Deficient Severe Combined Immunodeficiency: a Single Center Report

Hematopoietic stem cell transplantation (HSCT) is curative for severe combined immunodeficiency (SCID), but data on long-term impact of pre-HSCT chemotherapy, immune reconstitution and quality of life (QoL) of specific SCID genotypes are limited. We evaluated the long-term immune-reconstitution, hea...

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Veröffentlicht in:	Journal of clinical immunology 2018-08, Vol.38 (6), p.727-732
Hauptverfasser:	Abd Hamid, Intan Juliana, Slatter, Mary A., McKendrick, Fiona, Pearce, Mark S., Gennery, Andrew R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine CD4 antigen Chemotherapy Chimerism Genotypes Hematopoietic stem cells Immune reconstitution Immunology Infectious Diseases Internal Medicine Lymphocytes Medical Microbiology Original Article Quality of life RAG1 protein RAG2 protein Severe combined immunodeficiency Stem cell transplantation Thymopoiesis
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