Yeast red pigment modifies cloned human α-synuclein pathogenesis in Parkinson disease models in Saccharomyces cerevisiae and Drosophila melanogaster

Recently, we identified the yeast red pigment (RP), a polymer of 1-(5′-Phosphoribosyl)-5-aminoimidazole, as a novel potential anti-amyloid agent for the therapy of neurodegenerative diseases. The purpose of this study was to further validate RP for treatment of Parkinson's disease (PD) and to c...

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Veröffentlicht in:	Neurochemistry international 2018-11, Vol.120, p.172-181
Hauptverfasser:	Nevzglyadova, O.V., Mikhailova, E.V., Artemov, A.V., Ozerova, Y.E., Ivanova, P.A., Golomidov, I.M., Bolshakova, O.I., Zenin, V.V., Kostyleva, E.I., Soidla, T.R., Sarantseva, S.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid Drosophila Parkinson's disease Red pigment Yeast α-synuclein
Online-Zugang:	Volltext
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