Protease-activated receptor-2 activation: a major actor in intestinal inflammation

Background and aims:The role of protease-activated receptor-2 (PAR2) during intestinal inflammation is still unclear due to the fact that PAR2-activating peptide has both pro- and anti-inflammatory properties. The aim of this study was to investigate the effects of PAR2 deficiency (using PAR2-defici...

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Veröffentlicht in:	Gut 2008-09, Vol.57 (9), p.1222-1229
Hauptverfasser:	Hyun, E, Andrade-Gordon, P, Steinhoff, M, Vergnolle, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Adhesion Molecules - metabolism Colitis - chemically induced Colitis - metabolism Colitis - pathology Colon Cytokines Dextran Sulfate Disease Models, Animal Endothelium Gastroenterology. Liver. Pancreas. Abdomen Inflammation Inflammatory bowel disease Ligands Medical sciences Mice Mice, Inbred C57BL Microscopy Mortality Oxazolone Peroxidase - metabolism Prostaglandin-Endoperoxide Synthases - metabolism Receptor, PAR-2 - deficiency Receptor, PAR-2 - metabolism Receptor, PAR-2 - physiology Rodents Studies Trinitrobenzenesulfonic Acid
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