Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial
The optimal revascularization strategy for patients with left main coronary artery disease (LMCAD) and chronic kidney disease (CKD) remains unclear. This study investigated the comparative effectiveness of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2018-08, Vol.72 (7), p.754-765 |
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| creator | Giustino, Gennaro Mehran, Roxana Serruys, Patrick W Sabik, 3rd, Joseph F Milojevic, Milan Simonton, Charles A Puskas, John D Kandzari, David E Morice, Marie-Claude Taggart, David P Gershlick, Anthony H Généreux, Philippe Zhang, Zixuan McAndrew, Thomas Redfors, Björn Ragosta, 3rd, Michael Kron, Irving L Dressler, Ovidiu Leon, Martin B Pocock, Stuart J Ben-Yehuda, Ori Kappetein, Arie Pieter Stone, Gregg W |
| description | The optimal revascularization strategy for patients with left main coronary artery disease (LMCAD) and chronic kidney disease (CKD) remains unclear.
This study investigated the comparative effectiveness of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in patients with LMCAD and low or intermediate anatomical complexity according to baseline renal function from the multicenter randomized EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial.
CKD was defined as an estimated glomerular filtration rate |
| doi_str_mv | 10.1016/j.jacc.2018.05.057 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_2087594460</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2087594460</sourcerecordid><originalsourceid>FETCH-LOGICAL-p239t-e068a669855652bca266e37e83864c00ab48f118252475d278646abb349a6c253</originalsourceid><addsrcrecordid>eNpd0E1Lw0AQBuBFFFurf8CDLHjxkrjfH95qrFWMWKSit7BJt3RDmtRsItRf70rrRRgYmHkYXgaAc4xijLC4LuPSFEVMEFYx4qHkARhizlVEuZaHYIgk5RFGWg7AifclQkgorI_BgCKkieZkCExqlx18Nq6Gr_bL-KKvTOu-TeeaGr67bgVnySNsWpiMb6cwqFlY2brzu2WyapvaFfDJLWq7hXfOW-PtDZx8JJMUzltnqlNwtDSVt2f7PgJv95N58hClL9PHZJxGG0J1F9mQzQihFeeCk7wwRAhLpVVUCVYgZHKmlhgrwgmTfEFkGAuT55RpIwrC6Qhc7e5u2uazt77L1s4XtqpMbZveZwQpyTVjAgV6-Y-WTd_WId2vYkRJxnRQF3vV52u7yDatW5t2m_09j_4A8YtuFw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2084287449</pqid></control><display><type>article</type><title>Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial</title><source>Elsevier ScienceDirect Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Giustino, Gennaro ; Mehran, Roxana ; Serruys, Patrick W ; Sabik, 3rd, Joseph F ; Milojevic, Milan ; Simonton, Charles A ; Puskas, John D ; Kandzari, David E ; Morice, Marie-Claude ; Taggart, David P ; Gershlick, Anthony H ; Généreux, Philippe ; Zhang, Zixuan ; McAndrew, Thomas ; Redfors, Björn ; Ragosta, 3rd, Michael ; Kron, Irving L ; Dressler, Ovidiu ; Leon, Martin B ; Pocock, Stuart J ; Ben-Yehuda, Ori ; Kappetein, Arie Pieter ; Stone, Gregg W</creator><creatorcontrib>Giustino, Gennaro ; Mehran, Roxana ; Serruys, Patrick W ; Sabik, 3rd, Joseph F ; Milojevic, Milan ; Simonton, Charles A ; Puskas, John D ; Kandzari, David E ; Morice, Marie-Claude ; Taggart, David P ; Gershlick, Anthony H ; Généreux, Philippe ; Zhang, Zixuan ; McAndrew, Thomas ; Redfors, Björn ; Ragosta, 3rd, Michael ; Kron, Irving L ; Dressler, Ovidiu ; Leon, Martin B ; Pocock, Stuart J ; Ben-Yehuda, Ori ; Kappetein, Arie Pieter ; Stone, Gregg W</creatorcontrib><description>The optimal revascularization strategy for patients with left main coronary artery disease (LMCAD) and chronic kidney disease (CKD) remains unclear.
This study investigated the comparative effectiveness of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in patients with LMCAD and low or intermediate anatomical complexity according to baseline renal function from the multicenter randomized EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial.
CKD was defined as an estimated glomerular filtration rate <60 ml/min/1.73 m
using the CKD Epidemiology Collaboration equation. Acute renal failure (ARF) was defined as a serum creatinine increase ≥5.0 mg/dl from baseline or a new requirement for dialysis. The primary composite endpoint was the composite of death, myocardial infarction (MI), or stroke at 3-year follow-up.
CKD was present in 361 of 1,869 randomized patients (19.3%) in whom baseline estimated glomerular filtration rate was available. Patients with CKD had higher 3-year rates of the primary endpoint compared with those without CKD (20.8% vs. 13.5%; hazard ratio [HR]: 1.60; 95% confidence interval [CI]: 1.22 to 2.09; p = 0.0005). ARF within 30 days occurred more commonly in patients with compared with those without CKD (5.0% vs. 0.8%; p < 0.0001), and was strongly associated with the 3-year risk of death, stroke, or MI (50.7% vs. 14.4%; HR: 4.59; 95% CI: 2.73 to 7.73; p < 0.0001). ARF occurred less commonly after revascularization with PCI compared with CABG both in patients with CKD (2.3% vs. 7.7%; HR: 0.28; 95% CI: 0.09 to 0.87) and in those without CKD (0.3% vs. 1.3%; HR: 0.20; 95% CI: 0.04 to 0.90; p
= 0.71). There were no significant differences in the rates of the primary composite endpoint after PCI and CABG in patients with CKD (23.4% vs. 18.1%; HR: 1.25; 95% CI: 0.79 to 1.98) and without CKD (13.4% vs. 13.5%; HR: 0.97; 95% CI: 0.73 to 1.27; p
= 0.38).
Patients with CKD undergoing revascularization for LMCAD in the EXCEL trial had increased rates of ARF and reduced event-free survival. ARF occurred less frequently after PCI compared with CABG. There were no significant differences between PCI and CABG in terms of death, stroke, or MI at 3 years in patients with and without CKD. (EXCEL Clinical Trial [EXCEL]; NCT01205776).</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2018.05.057</identifier><identifier>PMID: 30092952</identifier><language>eng</language><publisher>United States: Elsevier Limited</publisher><subject>Cardiology ; Cardiovascular disease ; Cerebral infarction ; Confidence intervals ; Coronary artery ; Coronary artery disease ; Coronary vessels ; Creatinine ; Death ; Dialysis ; Epidemiology ; Glomerular filtration rate ; Health risks ; Heart attacks ; Heart diseases ; Heart surgery ; Ischemia ; Kidney diseases ; Kidneys ; Medical prognosis ; Mortality ; Myocardial infarction ; Patients ; Peritoneal dialysis ; Randomization ; Renal failure ; Renal function ; Stents ; Stroke ; Surgery ; Thrombosis</subject><ispartof>Journal of the American College of Cardiology, 2018-08, Vol.72 (7), p.754-765</ispartof><rights>Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Aug 14, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30092952$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giustino, Gennaro</creatorcontrib><creatorcontrib>Mehran, Roxana</creatorcontrib><creatorcontrib>Serruys, Patrick W</creatorcontrib><creatorcontrib>Sabik, 3rd, Joseph F</creatorcontrib><creatorcontrib>Milojevic, Milan</creatorcontrib><creatorcontrib>Simonton, Charles A</creatorcontrib><creatorcontrib>Puskas, John D</creatorcontrib><creatorcontrib>Kandzari, David E</creatorcontrib><creatorcontrib>Morice, Marie-Claude</creatorcontrib><creatorcontrib>Taggart, David P</creatorcontrib><creatorcontrib>Gershlick, Anthony H</creatorcontrib><creatorcontrib>Généreux, Philippe</creatorcontrib><creatorcontrib>Zhang, Zixuan</creatorcontrib><creatorcontrib>McAndrew, Thomas</creatorcontrib><creatorcontrib>Redfors, Björn</creatorcontrib><creatorcontrib>Ragosta, 3rd, Michael</creatorcontrib><creatorcontrib>Kron, Irving L</creatorcontrib><creatorcontrib>Dressler, Ovidiu</creatorcontrib><creatorcontrib>Leon, Martin B</creatorcontrib><creatorcontrib>Pocock, Stuart J</creatorcontrib><creatorcontrib>Ben-Yehuda, Ori</creatorcontrib><creatorcontrib>Kappetein, Arie Pieter</creatorcontrib><creatorcontrib>Stone, Gregg W</creatorcontrib><title>Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>The optimal revascularization strategy for patients with left main coronary artery disease (LMCAD) and chronic kidney disease (CKD) remains unclear.
This study investigated the comparative effectiveness of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in patients with LMCAD and low or intermediate anatomical complexity according to baseline renal function from the multicenter randomized EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial.
CKD was defined as an estimated glomerular filtration rate <60 ml/min/1.73 m
using the CKD Epidemiology Collaboration equation. Acute renal failure (ARF) was defined as a serum creatinine increase ≥5.0 mg/dl from baseline or a new requirement for dialysis. The primary composite endpoint was the composite of death, myocardial infarction (MI), or stroke at 3-year follow-up.
CKD was present in 361 of 1,869 randomized patients (19.3%) in whom baseline estimated glomerular filtration rate was available. Patients with CKD had higher 3-year rates of the primary endpoint compared with those without CKD (20.8% vs. 13.5%; hazard ratio [HR]: 1.60; 95% confidence interval [CI]: 1.22 to 2.09; p = 0.0005). ARF within 30 days occurred more commonly in patients with compared with those without CKD (5.0% vs. 0.8%; p < 0.0001), and was strongly associated with the 3-year risk of death, stroke, or MI (50.7% vs. 14.4%; HR: 4.59; 95% CI: 2.73 to 7.73; p < 0.0001). ARF occurred less commonly after revascularization with PCI compared with CABG both in patients with CKD (2.3% vs. 7.7%; HR: 0.28; 95% CI: 0.09 to 0.87) and in those without CKD (0.3% vs. 1.3%; HR: 0.20; 95% CI: 0.04 to 0.90; p
= 0.71). There were no significant differences in the rates of the primary composite endpoint after PCI and CABG in patients with CKD (23.4% vs. 18.1%; HR: 1.25; 95% CI: 0.79 to 1.98) and without CKD (13.4% vs. 13.5%; HR: 0.97; 95% CI: 0.73 to 1.27; p
= 0.38).
Patients with CKD undergoing revascularization for LMCAD in the EXCEL trial had increased rates of ARF and reduced event-free survival. ARF occurred less frequently after PCI compared with CABG. There were no significant differences between PCI and CABG in terms of death, stroke, or MI at 3 years in patients with and without CKD. (EXCEL Clinical Trial [EXCEL]; NCT01205776).</description><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Cerebral infarction</subject><subject>Confidence intervals</subject><subject>Coronary artery</subject><subject>Coronary artery disease</subject><subject>Coronary vessels</subject><subject>Creatinine</subject><subject>Death</subject><subject>Dialysis</subject><subject>Epidemiology</subject><subject>Glomerular filtration rate</subject><subject>Health risks</subject><subject>Heart attacks</subject><subject>Heart diseases</subject><subject>Heart surgery</subject><subject>Ischemia</subject><subject>Kidney diseases</subject><subject>Kidneys</subject><subject>Medical prognosis</subject><subject>Mortality</subject><subject>Myocardial infarction</subject><subject>Patients</subject><subject>Peritoneal dialysis</subject><subject>Randomization</subject><subject>Renal failure</subject><subject>Renal function</subject><subject>Stents</subject><subject>Stroke</subject><subject>Surgery</subject><subject>Thrombosis</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNpd0E1Lw0AQBuBFFFurf8CDLHjxkrjfH95qrFWMWKSit7BJt3RDmtRsItRf70rrRRgYmHkYXgaAc4xijLC4LuPSFEVMEFYx4qHkARhizlVEuZaHYIgk5RFGWg7AifclQkgorI_BgCKkieZkCExqlx18Nq6Gr_bL-KKvTOu-TeeaGr67bgVnySNsWpiMb6cwqFlY2brzu2WyapvaFfDJLWq7hXfOW-PtDZx8JJMUzltnqlNwtDSVt2f7PgJv95N58hClL9PHZJxGG0J1F9mQzQihFeeCk7wwRAhLpVVUCVYgZHKmlhgrwgmTfEFkGAuT55RpIwrC6Qhc7e5u2uazt77L1s4XtqpMbZveZwQpyTVjAgV6-Y-WTd_WId2vYkRJxnRQF3vV52u7yDatW5t2m_09j_4A8YtuFw</recordid><startdate>20180814</startdate><enddate>20180814</enddate><creator>Giustino, Gennaro</creator><creator>Mehran, Roxana</creator><creator>Serruys, Patrick W</creator><creator>Sabik, 3rd, Joseph F</creator><creator>Milojevic, Milan</creator><creator>Simonton, Charles A</creator><creator>Puskas, John D</creator><creator>Kandzari, David E</creator><creator>Morice, Marie-Claude</creator><creator>Taggart, David P</creator><creator>Gershlick, Anthony H</creator><creator>Généreux, Philippe</creator><creator>Zhang, Zixuan</creator><creator>McAndrew, Thomas</creator><creator>Redfors, Björn</creator><creator>Ragosta, 3rd, Michael</creator><creator>Kron, Irving L</creator><creator>Dressler, Ovidiu</creator><creator>Leon, Martin B</creator><creator>Pocock, Stuart J</creator><creator>Ben-Yehuda, Ori</creator><creator>Kappetein, Arie Pieter</creator><creator>Stone, Gregg W</creator><general>Elsevier Limited</general><scope>NPM</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20180814</creationdate><title>Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial</title><author>Giustino, Gennaro ; Mehran, Roxana ; Serruys, Patrick W ; Sabik, 3rd, Joseph F ; Milojevic, Milan ; Simonton, Charles A ; Puskas, John D ; Kandzari, David E ; Morice, Marie-Claude ; Taggart, David P ; Gershlick, Anthony H ; Généreux, Philippe ; Zhang, Zixuan ; McAndrew, Thomas ; Redfors, Björn ; Ragosta, 3rd, Michael ; Kron, Irving L ; Dressler, Ovidiu ; Leon, Martin B ; Pocock, Stuart J ; Ben-Yehuda, Ori ; Kappetein, Arie Pieter ; Stone, Gregg W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p239t-e068a669855652bca266e37e83864c00ab48f118252475d278646abb349a6c253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Cerebral infarction</topic><topic>Confidence intervals</topic><topic>Coronary artery</topic><topic>Coronary artery disease</topic><topic>Coronary vessels</topic><topic>Creatinine</topic><topic>Death</topic><topic>Dialysis</topic><topic>Epidemiology</topic><topic>Glomerular filtration rate</topic><topic>Health risks</topic><topic>Heart attacks</topic><topic>Heart diseases</topic><topic>Heart surgery</topic><topic>Ischemia</topic><topic>Kidney diseases</topic><topic>Kidneys</topic><topic>Medical prognosis</topic><topic>Mortality</topic><topic>Myocardial infarction</topic><topic>Patients</topic><topic>Peritoneal dialysis</topic><topic>Randomization</topic><topic>Renal failure</topic><topic>Renal function</topic><topic>Stents</topic><topic>Stroke</topic><topic>Surgery</topic><topic>Thrombosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giustino, Gennaro</creatorcontrib><creatorcontrib>Mehran, Roxana</creatorcontrib><creatorcontrib>Serruys, Patrick W</creatorcontrib><creatorcontrib>Sabik, 3rd, Joseph F</creatorcontrib><creatorcontrib>Milojevic, Milan</creatorcontrib><creatorcontrib>Simonton, Charles A</creatorcontrib><creatorcontrib>Puskas, John D</creatorcontrib><creatorcontrib>Kandzari, David E</creatorcontrib><creatorcontrib>Morice, Marie-Claude</creatorcontrib><creatorcontrib>Taggart, David P</creatorcontrib><creatorcontrib>Gershlick, Anthony H</creatorcontrib><creatorcontrib>Généreux, Philippe</creatorcontrib><creatorcontrib>Zhang, Zixuan</creatorcontrib><creatorcontrib>McAndrew, Thomas</creatorcontrib><creatorcontrib>Redfors, Björn</creatorcontrib><creatorcontrib>Ragosta, 3rd, Michael</creatorcontrib><creatorcontrib>Kron, Irving L</creatorcontrib><creatorcontrib>Dressler, Ovidiu</creatorcontrib><creatorcontrib>Leon, Martin B</creatorcontrib><creatorcontrib>Pocock, Stuart J</creatorcontrib><creatorcontrib>Ben-Yehuda, Ori</creatorcontrib><creatorcontrib>Kappetein, Arie Pieter</creatorcontrib><creatorcontrib>Stone, Gregg W</creatorcontrib><collection>PubMed</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giustino, Gennaro</au><au>Mehran, Roxana</au><au>Serruys, Patrick W</au><au>Sabik, 3rd, Joseph F</au><au>Milojevic, Milan</au><au>Simonton, Charles A</au><au>Puskas, John D</au><au>Kandzari, David E</au><au>Morice, Marie-Claude</au><au>Taggart, David P</au><au>Gershlick, Anthony H</au><au>Généreux, Philippe</au><au>Zhang, Zixuan</au><au>McAndrew, Thomas</au><au>Redfors, Björn</au><au>Ragosta, 3rd, Michael</au><au>Kron, Irving L</au><au>Dressler, Ovidiu</au><au>Leon, Martin B</au><au>Pocock, Stuart J</au><au>Ben-Yehuda, Ori</au><au>Kappetein, Arie Pieter</au><au>Stone, Gregg W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2018-08-14</date><risdate>2018</risdate><volume>72</volume><issue>7</issue><spage>754</spage><epage>765</epage><pages>754-765</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>The optimal revascularization strategy for patients with left main coronary artery disease (LMCAD) and chronic kidney disease (CKD) remains unclear.
This study investigated the comparative effectiveness of percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery in patients with LMCAD and low or intermediate anatomical complexity according to baseline renal function from the multicenter randomized EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial.
CKD was defined as an estimated glomerular filtration rate <60 ml/min/1.73 m
using the CKD Epidemiology Collaboration equation. Acute renal failure (ARF) was defined as a serum creatinine increase ≥5.0 mg/dl from baseline or a new requirement for dialysis. The primary composite endpoint was the composite of death, myocardial infarction (MI), or stroke at 3-year follow-up.
CKD was present in 361 of 1,869 randomized patients (19.3%) in whom baseline estimated glomerular filtration rate was available. Patients with CKD had higher 3-year rates of the primary endpoint compared with those without CKD (20.8% vs. 13.5%; hazard ratio [HR]: 1.60; 95% confidence interval [CI]: 1.22 to 2.09; p = 0.0005). ARF within 30 days occurred more commonly in patients with compared with those without CKD (5.0% vs. 0.8%; p < 0.0001), and was strongly associated with the 3-year risk of death, stroke, or MI (50.7% vs. 14.4%; HR: 4.59; 95% CI: 2.73 to 7.73; p < 0.0001). ARF occurred less commonly after revascularization with PCI compared with CABG both in patients with CKD (2.3% vs. 7.7%; HR: 0.28; 95% CI: 0.09 to 0.87) and in those without CKD (0.3% vs. 1.3%; HR: 0.20; 95% CI: 0.04 to 0.90; p
= 0.71). There were no significant differences in the rates of the primary composite endpoint after PCI and CABG in patients with CKD (23.4% vs. 18.1%; HR: 1.25; 95% CI: 0.79 to 1.98) and without CKD (13.4% vs. 13.5%; HR: 0.97; 95% CI: 0.73 to 1.27; p
= 0.38).
Patients with CKD undergoing revascularization for LMCAD in the EXCEL trial had increased rates of ARF and reduced event-free survival. ARF occurred less frequently after PCI compared with CABG. There were no significant differences between PCI and CABG in terms of death, stroke, or MI at 3 years in patients with and without CKD. (EXCEL Clinical Trial [EXCEL]; NCT01205776).</abstract><cop>United States</cop><pub>Elsevier Limited</pub><pmid>30092952</pmid><doi>10.1016/j.jacc.2018.05.057</doi><tpages>12</tpages></addata></record> |
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| source | Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Cardiology Cardiovascular disease Cerebral infarction Confidence intervals Coronary artery Coronary artery disease Coronary vessels Creatinine Death Dialysis Epidemiology Glomerular filtration rate Health risks Heart attacks Heart diseases Heart surgery Ischemia Kidney diseases Kidneys Medical prognosis Mortality Myocardial infarction Patients Peritoneal dialysis Randomization Renal failure Renal function Stents Stroke Surgery Thrombosis |
| title | Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial |
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