Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

Changes to the microenvironment of pancreatic ductal adenocarcinomas (PDACs) have been associated with poor outcomes of patients. We studied the associations between composition of the pancreatic stroma (fibrogenic, inert, dormant, or fibrolytic stroma) and infiltration by inflammatory cells and tim...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2018-11, Vol.155 (5), p.1625-1639.e2
Hauptverfasser:	Mahajan, Ujjwal Mukund, Langhoff, Eno, Goni, Elisabetta, Costello, Eithne, Greenhalf, William, Halloran, Christopher, Ormanns, Steffen, Kruger, Stephan, Boeck, Stefan, Ribback, Silvia, Beyer, Georg, Dombroswki, Frank, Weiss, Frank-Ulrich, Neoptolemos, John P., Werner, Jens, D’Haese, Jan G., Bazhin, Alexandr, Peterhansl, Julian, Pichlmeier, Svenja, Büchler, Markus W., Kleeff, Jörg, Ganeh, Paula, Sendler, Matthias, Palmer, Daniel H., Kohlmann, Thomas, Rad, Roland, Regel, Ivonne, Lerch, Markus M., Mayerle, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - immunology Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - surgery Adult Aged Aged, 80 and over Antigens, CD - analysis Carcinoma, Pancreatic Ductal - immunology Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - surgery Disease-Free Survival ESPAC Female Histologic Analysis Humans Lymphocytes, Tumor-Infiltrating - immunology Male Middle Aged Pancreatic Cancer Pancreatic Neoplasms - immunology Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - surgery Prognostic Factor
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