Regulation of CB1cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism

Agonists stimulate cannabinoid 1 receptor (CB1R) internalization. Previous work suggests that the extreme carboxy-terminus of the receptor regulates this internalization - likely through the phosphorylation of serines and threonines clustered within this region. While truncation of the carboxy-termi...

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Veröffentlicht in:Journal of neurochemistry 2008-07, Vol.106 (1), p.70-82
Hauptverfasser: Daigle, Tanya L, Kwok, Mary Lee, Mackie, Ken
Format: Artikel
Sprache:eng
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