Disposition and metabolic profiling of [14C]-Decabromodiphenyl ether in pregnant Wistar rats

Fully brominated diphenyl ether, decabromodiphenyl ether (DBDE), is one of the most widely used brominated flame retardants worldwide. Little data is available about the metabolic fate of DBDE in animal models and nothing at all about the extent of foetal exposure. In this work, pregnant Wistar rats...

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Veröffentlicht in:	Environment international 2008-04, Vol.34 (3), p.318-329
Hauptverfasser:	Riu, Anne, Cravedi, Jean-Pierre, Debrauwer, Laurent, Garcia, Aurélie, Canlet, Cécile, Jouanin, Isabelle, Zalko, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - chemistry Animals Biological and medical sciences Biotransformation Carbon Radioisotopes - metabolism Chemical and industrial products toxicology. Toxic occupational diseases Chromatography, Liquid DBDE Diphenyl ether Endocrine disrupter Endocrine Glands - chemistry Female Fetus - chemistry Flame Retardants - metabolism Foetus Halogenated Diphenyl Ethers In vivo Liver - chemistry Magnetic Resonance Spectroscopy Mass Spectrometry Medical sciences Metabolism Molecular Structure Oxidation-Reduction PBDEs Phenyl Ethers - metabolism Polybrominated Biphenyls - metabolism Pregnancy Rat Rats Rats, Wistar Staining and Labeling Toxicology Various organic compounds
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