High resolution pHe imaging of rat glioma using pH-dependent relaxivity

Previous studies using MR spectroscopy have shown that the extracellular pH (pHe) of tumors is acidic compared to normal tissues. This has a number of important sequelae that favor the emergence of more aggressive and therapy‐resistant tumors. New MRI methods based on pH‐sensitive T1 relaxivity are...

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Veröffentlicht in:	Magnetic resonance in medicine 2006-02, Vol.55 (2), p.309-315
Hauptverfasser:	Garcia-Martin, Maria L., Martinez, Gary V., Raghunand, Natarajan, Sherry, A. Dean, Zhang, Shanrong, Gillies, Robert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	acid-base gadolinium MRI relaxivity tumor tumor, pH
Online-Zugang:	Volltext
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