Detection of low-level environmental chemical allergy by a long-term sensitization method

Multiple chemical sensitivity (MCS) is characterized by various signs, including neurological disorders and allergy. Exposure may occur through a major event, such as a chemical spill, or from long-term contact with chemicals at low levels. We are interested in the allergenicity of MCS and the detec...

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Veröffentlicht in:	Toxicology letters 2008-07, Vol.180 (1), p.1-8
Hauptverfasser:	Fukuyama, Tomoki, Ueda, Hideo, Hayashi, Koichi, Tajima, Yukari, Shuto, Yasufumi, Saito, Toru R., Harada, Takanori, Kosaka, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	2,4-Dinitrochlorobenzene Allergens - immunology Animals B-Lymphocytes - drug effects B-Lymphocytes - immunology B-Lymphocytes - metabolism BALB/c mouse Biological and medical sciences Cytokines - metabolism Dinitrochlorobenzene - immunology Disease Models, Animal Dose-Response Relationship, Drug Female Immunization Immunoglobulin E - blood Local Lymph Node Assay Lymph Nodes - drug effects Lymph Nodes - immunology Lymph Nodes - pathology Lymphocyte Activation - drug effects Lymphocyte Activation - immunology Lymphocytes - drug effects Lymphocytes - immunology Lymphocytes - metabolism Medical sciences Mice Mice, Inbred BALB C Multiple chemical sensitivity Multiple Chemical Sensitivity - blood Multiple Chemical Sensitivity - immunology Multiple Chemical Sensitivity - pathology Phthalic Anhydrides - immunology Toluene 2,4-Diisocyanate - immunology Toluene diisocyanate Toxicology Trimellitic anhydride
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