BODIPY-based fluorescent sensor for imaging of endogenous formaldehyde in living cells
A new highly selective fluorescent chemosensor for formaldehyde (FA) has been synthesized based on boron dipyrromethene as fluorophore and o-phenylenediamine (OPDA) as reaction group. When FA is added, the fluorescence emission band of the chemosensor red shift (from 525 nm to 548 nm) accompanied by...
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Veröffentlicht in: | Talanta (Oxford) 2018-11, Vol.189, p.274-280 |
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creator | Cao, Ting Gong, Deyan Han, Shi-Chong Iqbal, Anam Qian, Jing Liu, Wei Qin, Wenwu Guo, Huichen |
description | A new highly selective fluorescent chemosensor for formaldehyde (FA) has been synthesized based on boron dipyrromethene as fluorophore and o-phenylenediamine (OPDA) as reaction group. When FA is added, the fluorescence emission band of the chemosensor red shift (from 525 nm to 548 nm) accompanied by an increase in intensity with strong green fluorescence was observed. This chemosensor also exhibited the lowest detection limit (0.104 μM) distinguished with other articles that have been reported. The application to cellular fluorescence imaging or test papers detection both indicated that the probe was highly responsive to the FA in endogenous cells and in the gaseous environment.
[Display omitted]
•Bodipy-OPDA exhibits very low detection limit (0.104 μM) for detecting formaldehyde compare with others.•Bodipy-OPDA can be used monitoring and imaging exogenously and endogenously.•formaldehyde in living cells.•Bodipy-OPDA is also effective and keen to detect formaldehyde in the gas environment. |
doi_str_mv | 10.1016/j.talanta.2018.07.001 |
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[Display omitted]
•Bodipy-OPDA exhibits very low detection limit (0.104 μM) for detecting formaldehyde compare with others.•Bodipy-OPDA can be used monitoring and imaging exogenously and endogenously.•formaldehyde in living cells.•Bodipy-OPDA is also effective and keen to detect formaldehyde in the gas environment.</description><identifier>ISSN: 0039-9140</identifier><identifier>EISSN: 1873-3573</identifier><identifier>DOI: 10.1016/j.talanta.2018.07.001</identifier><identifier>PMID: 30086918</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>BODIPY ; Endogenous and exogenous ; Fluorescent sensor ; Formaldehyde ; Gaseous detection</subject><ispartof>Talanta (Oxford), 2018-11, Vol.189, p.274-280</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-4d31fcb27f994af3ff4de663e9d5097dfa8ca4f2d6b7e157372f9bcfd3e4b8ef3</citedby><cites>FETCH-LOGICAL-c365t-4d31fcb27f994af3ff4de663e9d5097dfa8ca4f2d6b7e157372f9bcfd3e4b8ef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.talanta.2018.07.001$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30086918$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cao, Ting</creatorcontrib><creatorcontrib>Gong, Deyan</creatorcontrib><creatorcontrib>Han, Shi-Chong</creatorcontrib><creatorcontrib>Iqbal, Anam</creatorcontrib><creatorcontrib>Qian, Jing</creatorcontrib><creatorcontrib>Liu, Wei</creatorcontrib><creatorcontrib>Qin, Wenwu</creatorcontrib><creatorcontrib>Guo, Huichen</creatorcontrib><title>BODIPY-based fluorescent sensor for imaging of endogenous formaldehyde in living cells</title><title>Talanta (Oxford)</title><addtitle>Talanta</addtitle><description>A new highly selective fluorescent chemosensor for formaldehyde (FA) has been synthesized based on boron dipyrromethene as fluorophore and o-phenylenediamine (OPDA) as reaction group. When FA is added, the fluorescence emission band of the chemosensor red shift (from 525 nm to 548 nm) accompanied by an increase in intensity with strong green fluorescence was observed. This chemosensor also exhibited the lowest detection limit (0.104 μM) distinguished with other articles that have been reported. The application to cellular fluorescence imaging or test papers detection both indicated that the probe was highly responsive to the FA in endogenous cells and in the gaseous environment.
[Display omitted]
•Bodipy-OPDA exhibits very low detection limit (0.104 μM) for detecting formaldehyde compare with others.•Bodipy-OPDA can be used monitoring and imaging exogenously and endogenously.•formaldehyde in living cells.•Bodipy-OPDA is also effective and keen to detect formaldehyde in the gas environment.</description><subject>BODIPY</subject><subject>Endogenous and exogenous</subject><subject>Fluorescent sensor</subject><subject>Formaldehyde</subject><subject>Gaseous detection</subject><issn>0039-9140</issn><issn>1873-3573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqFkDtv2zAURokgRe04_QkpNGaRcilKojgFado8AAPp0AboRFDkpUtDphxSCpB_Xwp2umYg7sBzH98h5IJCQYE2V9tiVL3yoypKoG0BvACgJ2RJW85yVnN2SpYATOSCVrAgZzFuAaBkwD6TBQNoG0HbJXn-9vT98eefvFMRTWb7aQgYNfoxi-jjEDKbntupjfObbLAZejNs0A9TnH92qjf4981g5nzWu9cZ0tj38Zx8sqqP-OVYV-T33Y9ftw_5-un-8fZmnWvW1GNeGUat7kpuhaiUZdZWBpuGoTA1CG6sarWqbGmajiNNoXhpRaetYVh1LVq2IpeHufswvEwYR7lzcb5AeUw3yhLauql5K2hC6wOqwxBjQCv3IQULb5KCnJXKrTwqlbNSCVwmpanv63HF1O3Q_O96d5iA6wOAKeirwyCjdug1GhdQj9IM7oMV_wDF5Yv0</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Cao, Ting</creator><creator>Gong, Deyan</creator><creator>Han, Shi-Chong</creator><creator>Iqbal, Anam</creator><creator>Qian, Jing</creator><creator>Liu, Wei</creator><creator>Qin, Wenwu</creator><creator>Guo, Huichen</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20181101</creationdate><title>BODIPY-based fluorescent sensor for imaging of endogenous formaldehyde in living cells</title><author>Cao, Ting ; Gong, Deyan ; Han, Shi-Chong ; Iqbal, Anam ; Qian, Jing ; Liu, Wei ; Qin, Wenwu ; Guo, Huichen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-4d31fcb27f994af3ff4de663e9d5097dfa8ca4f2d6b7e157372f9bcfd3e4b8ef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>BODIPY</topic><topic>Endogenous and exogenous</topic><topic>Fluorescent sensor</topic><topic>Formaldehyde</topic><topic>Gaseous detection</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cao, Ting</creatorcontrib><creatorcontrib>Gong, Deyan</creatorcontrib><creatorcontrib>Han, Shi-Chong</creatorcontrib><creatorcontrib>Iqbal, Anam</creatorcontrib><creatorcontrib>Qian, Jing</creatorcontrib><creatorcontrib>Liu, Wei</creatorcontrib><creatorcontrib>Qin, Wenwu</creatorcontrib><creatorcontrib>Guo, Huichen</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Talanta (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cao, Ting</au><au>Gong, Deyan</au><au>Han, Shi-Chong</au><au>Iqbal, Anam</au><au>Qian, Jing</au><au>Liu, Wei</au><au>Qin, Wenwu</au><au>Guo, Huichen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BODIPY-based fluorescent sensor for imaging of endogenous formaldehyde in living cells</atitle><jtitle>Talanta (Oxford)</jtitle><addtitle>Talanta</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>189</volume><spage>274</spage><epage>280</epage><pages>274-280</pages><issn>0039-9140</issn><eissn>1873-3573</eissn><abstract>A new highly selective fluorescent chemosensor for formaldehyde (FA) has been synthesized based on boron dipyrromethene as fluorophore and o-phenylenediamine (OPDA) as reaction group. When FA is added, the fluorescence emission band of the chemosensor red shift (from 525 nm to 548 nm) accompanied by an increase in intensity with strong green fluorescence was observed. This chemosensor also exhibited the lowest detection limit (0.104 μM) distinguished with other articles that have been reported. The application to cellular fluorescence imaging or test papers detection both indicated that the probe was highly responsive to the FA in endogenous cells and in the gaseous environment.
[Display omitted]
•Bodipy-OPDA exhibits very low detection limit (0.104 μM) for detecting formaldehyde compare with others.•Bodipy-OPDA can be used monitoring and imaging exogenously and endogenously.•formaldehyde in living cells.•Bodipy-OPDA is also effective and keen to detect formaldehyde in the gas environment.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>30086918</pmid><doi>10.1016/j.talanta.2018.07.001</doi><tpages>7</tpages></addata></record> |
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source | ScienceDirect Journals (5 years ago - present) |
subjects | BODIPY Endogenous and exogenous Fluorescent sensor Formaldehyde Gaseous detection |
title | BODIPY-based fluorescent sensor for imaging of endogenous formaldehyde in living cells |
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