POLD1 and POLE Gene Mutations in Jewish Cohorts of Early-Onset Colorectal Cancer and of Multiple Colorectal Adenomas

BACKGROUND:Germline mutations in the DNA polymerase genes POLD1 and POLE confer high risk for multiple colorectal adenomas and colorectal cancer. However, prevalence and the clinical phenotype of mutation carriers are still not fully characterized. OBJECTIVE:The purpose of this study was to assess t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Diseases of the colon & rectum 2018-09, Vol.61 (9), p.1073-1079
Hauptverfasser:	Rosner, Guy, Gluck, Nathan, Carmi, Shai, Bercovich, Dani, Fliss-Issakov, Naomi, Ben-Yehoyada, Merav, Aharon-Caspi, Sivan, Kellerman, Efrat, Strul, Hana, Shibolet, Oren, Kariv, Revital
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!