A Novel Binding Factor of 14-3-3b Functions as a Transcriptional Repressor and Promotes Anchorage-independent Growth, Tumorigenicity, and Metastasis
The 14-3-3 proteins form a highly conserved family of dimeric proteins that interact with various signal transduction proteins and regulate cell cycle, apoptosis, stress response, and malignant transformation. We previously demonstrated that the b isoform of 14-3-3 proteins promotes tumorigenicity a...
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Veröffentlicht in: | The Journal of biological chemistry 2008-07, Vol.283 (27), p.18753-18764 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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