In Vivo Visualization of Locally Transplanted Mesenchymal Stem Cells in the Severely Injured Muscle in Rats

Autologous mesenchymal stem cells (MSCs) have been shown to improve the functional outcome after skeletal muscle trauma. The mechanisms behind this improvement have to be answered prior to a future clinical application. We investigated for the first time the in vivo distribution and behavior of MSCs...

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Veröffentlicht in:	Tissue engineering. Part A 2008-07, Vol.14 (7), p.1149-1160
Hauptverfasser:	Winkler, Tobias, von Roth, Philipp, Schumann, Maria Rose, Sieland, Katharina, Stoltenburg-Didinger, Gisela, Taupitz, Matthias, Perka, Carsten, Duda, Georg N., Matziolis, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cellular biology Diagnostic imaging Ferric Compounds Injuries Magnetic Resonance Imaging - methods Male Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - pathology Methods Muscle, Skeletal - injuries Muscle, Skeletal - pathology Muscle, Skeletal - physiopathology Muscular system Myofibrils - pathology Nanoparticles Physiological aspects Rats Rats, Sprague-Dawley Regeneration Regeneration (Biology) Rodents Stem cells Time Factors Tissue engineering Transplantation Transplants & implants Wounds and Injuries - pathology Wounds and Injuries - physiopathology Wounds and Injuries - therapy
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