Nitric oxide donor-based FFA1 agonists: Design, synthesis and biological evaluation as potential anti-diabetic and anti-thrombotic agents

[Display omitted] The cardiovascular complications were highly prevalent in type 2 diabetes mellitus (T2DM), even at the early stage of T2DM or the state of intensive glycemic control. Thus, there is an urgent need for the intervention of cardiovascular complications in T2DM. Herein, the new hybrids...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2018-08, Vol.26 (15), p.4560-4566
Hauptverfasser: Li, Zheng, Xu, Xue, Liu, Roujia, Deng, Fengjian, Zeng, Xiaohua, Zhang, Luyong
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Sprache:eng
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