Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation

Eosinophil cationic protein (ECP) is a ribonuclease secreted from activated eosinophils that may cause tissue injure as a result of eosinophilic inflammation. ECP possesses bactericidal, antiviral and helminthotoxic activity and inhibits mammalian cell growth. The mechanism by which ECP exerts its t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular and cellular biochemistry 2005-04, Vol.272 (1-2), p.1-7
Hauptverfasser:	Carreras, Esther, Boix, Ester, Navarro, Susanna, Rosenberg, Helene F, Cuchillo, Claudi M, Nogués, M Victòria
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Amino acids Amino Acids, Aromatic - chemistry Amino Acids, Aromatic - genetics Carbohydrates Cell growth Cell Proliferation - drug effects Eosinophil Cationic Protein - chemistry Eosinophil Cationic Protein - genetics Eosinophil Cationic Protein - pharmacology Humans Mammals Mutation Protein Conformation Proteins Residues Tryptophan - chemistry Tryptophan - genetics Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!