Neuroprotective effects of the cannabigerol quinone derivative VCE-003.2 in SOD1G93A transgenic mice, an experimental model of amyotrophic lateral sclerosis

[Display omitted] Antioxidant phytocannabinoids, synthetic compounds targeting the CB2 receptor, and inhibitors of the endocannabinoid inactivation afforded neuroprotection in SOD1G93A mutant mice, a model of ALS. These effects may involve the activation of PPAR-γ too. Here, we have investigated the...

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Veröffentlicht in:	Biochemical pharmacology 2018-11, Vol.157, p.217-226
Hauptverfasser:	Rodríguez-Cueto, Carmen, Santos-García, Irene, García-Toscano, Laura, Espejo-Porras, Francisco, Bellido, MLuz, Fernández-Ruiz, Javier, Muñoz, Eduardo, de Lago, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic lateral sclerosis Cannabinoids Neuroprotection PPAR-γ SOD-1 mutant mice VCE-003.2
Online-Zugang:	Volltext
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