Combination of flow cytometry and qPCR to study the immune response of american cutaneous leishmaniasis patients

American Cutaneous leishmaniasis (ACL) is a public health problem. The immunological response is mainly dependent on T cell cytokine responses and might influence disease presentation, susceptibility and development. The understanding of the host immune response role in the control and in the pathol...

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Veröffentlicht in:	Microbial pathogenesis 2018-10, Vol.123, p.433-439
Hauptverfasser:	Brelaz-de-Castro, Maria Carolina Accioly, de Almeida, Thays Miranda, de Almeida, Amanda Ferreira, de Assis Souza, Marina, de Oliveira Mendes, Andresa Pereira, Silva, Rafael de Freitas e, de Brito, Maria Edileuza Felinto, Pereira, Valéria Rêgo Alves
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult American cutaneous leishmaniasis Antigens, Protozoan - immunology Brazil CD4-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - metabolism Cell Culture Techniques Cytokines Cytokines - metabolism Flow cytometry Flow Cytometry - methods Humans Immune response Interferon-gamma - genetics Interferon-gamma - metabolism Interleukin-10 - metabolism Interleukin-4 - metabolism Leishmania braziliensis Leishmania braziliensis - immunology Leishmaniasis, Cutaneous - blood Leishmaniasis, Cutaneous - immunology Leukocytes, Mononuclear - metabolism Middle Aged Protozoan Proteins - immunology qPCR Real-Time Polymerase Chain Reaction - methods RNA, Messenger - metabolism T lymphocytes Young Adult
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