Reference Values for Mid-Ascending Aorta Diameters by Transthoracic Echocardiography in Adults
We sought to characterize mid-ascending aorta diameter reference values by age, sex, and body surface area (BSA) in a large echocardiography laboratory practice-based cohort. All subjects with transthoracic echocardiograms with mid-ascending aorta diameter measure from January 2004 to December 2009...
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| Veröffentlicht in: | The American journal of cardiology 2018-09, Vol.122 (6), p.1068-1073 |
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| container_title | The American journal of cardiology |
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| creator | Ayoub, Chadi Kumar, Gautam Smith, Carin Y. Bryant, Sandra C. Jech, Diane M. Ionescu, Filip Petrescu, Ioana Miller, Fletcher A. Spittell, Peter C. |
| description | We sought to characterize mid-ascending aorta diameter reference values by age, sex, and body surface area (BSA) in a large echocardiography laboratory practice-based cohort. All subjects with transthoracic echocardiograms with mid-ascending aorta diameter measure from January 2004 to December 2009 were identified, and medical records were reviewed for medical history and anthropometric data. Those with aortic valve disease or replacement, congenital heart disease, any connective tissue or inflammatory disease that may affect the aorta, or known aortic aneurysm (>55 mm) were excluded. Mid-ascending aorta diameter was measured in a standardized manner using "leading edge to leading edge" technique at end-diastole. Of 27,839 eligible subjects, 16,620 did not have history of hypertension and were included in the analysis (56.3% female; mean age 52.0 ± 15.8 years), mean mid-ascending aorta diameter 31.7 ± 4.1 mm. Females had smaller diameter than males (30.5 ± 3.7 mm vs 33.3 ± 4.0 mm; p |
| doi_str_mv | 10.1016/j.amjcard.2018.06.006 |
| format | Article |
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All subjects with transthoracic echocardiograms with mid-ascending aorta diameter measure from January 2004 to December 2009 were identified, and medical records were reviewed for medical history and anthropometric data. Those with aortic valve disease or replacement, congenital heart disease, any connective tissue or inflammatory disease that may affect the aorta, or known aortic aneurysm (>55 mm) were excluded. Mid-ascending aorta diameter was measured in a standardized manner using "leading edge to leading edge" technique at end-diastole. Of 27,839 eligible subjects, 16,620 did not have history of hypertension and were included in the analysis (56.3% female; mean age 52.0 ± 15.8 years), mean mid-ascending aorta diameter 31.7 ± 4.1 mm. Females had smaller diameter than males (30.5 ± 3.7 mm vs 33.3 ± 4.0 mm; p <0.001). Subjects with history of hypertension (n = 11,219; not included in the analysis) had larger mid-ascending aorta diameter compared with normotensive subjects (33.9 ± 3.8 mm vs 31.7 ± 4.1 mm; p < 0.001). Age had the greatest correlation with aortic size (r = 0.55), followed by sex (r = 0.35) and BSA (r = 0.35). Nomograms for predicted mid-ascending aorta diameter were generated at the 95th percentile using quantile regression for subjects without hypertension stratified by age, sex, and BSA. In conclusion, mid-ascending aorta diameter is predominantly associated with sex, age, and BSA. The nomograms established by this study may serve as useful reference values for echocardiographic screening and surveillance.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2018.06.006</identifier><identifier>PMID: 30075888</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adults ; Age ; Anthropometry ; Aorta ; Aortic valve ; Blood pressure ; Body mass index ; Cardiovascular disease ; Connective tissues ; Coronary artery disease ; Coronary vessels ; Diabetes ; Diastole ; Echocardiography ; Ethnicity ; Females ; Heart diseases ; Heart rate ; Hypertension ; Laboratories ; Males ; Medical records ; NMR ; Nomograms ; Nuclear magnetic resonance ; Patients ; Regression analysis ; Rheumatic heart disease ; Sex ; Ultrasonic imaging</subject><ispartof>The American journal of cardiology, 2018-09, Vol.122 (6), p.1068-1073</ispartof><rights>2018</rights><rights>Copyright © 2018. Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Sep 15, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-c9e90fa5562d2682192a03e4a65b097559228cd308b7948b87f20dc4f28593e73</citedby><cites>FETCH-LOGICAL-c393t-c9e90fa5562d2682192a03e4a65b097559228cd308b7948b87f20dc4f28593e73</cites><orcidid>0000-0002-7118-2302</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002914918312414$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30075888$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ayoub, Chadi</creatorcontrib><creatorcontrib>Kumar, Gautam</creatorcontrib><creatorcontrib>Smith, Carin Y.</creatorcontrib><creatorcontrib>Bryant, Sandra C.</creatorcontrib><creatorcontrib>Jech, Diane M.</creatorcontrib><creatorcontrib>Ionescu, Filip</creatorcontrib><creatorcontrib>Petrescu, Ioana</creatorcontrib><creatorcontrib>Miller, Fletcher A.</creatorcontrib><creatorcontrib>Spittell, Peter C.</creatorcontrib><title>Reference Values for Mid-Ascending Aorta Diameters by Transthoracic Echocardiography in Adults</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>We sought to characterize mid-ascending aorta diameter reference values by age, sex, and body surface area (BSA) in a large echocardiography laboratory practice-based cohort. All subjects with transthoracic echocardiograms with mid-ascending aorta diameter measure from January 2004 to December 2009 were identified, and medical records were reviewed for medical history and anthropometric data. Those with aortic valve disease or replacement, congenital heart disease, any connective tissue or inflammatory disease that may affect the aorta, or known aortic aneurysm (>55 mm) were excluded. Mid-ascending aorta diameter was measured in a standardized manner using "leading edge to leading edge" technique at end-diastole. Of 27,839 eligible subjects, 16,620 did not have history of hypertension and were included in the analysis (56.3% female; mean age 52.0 ± 15.8 years), mean mid-ascending aorta diameter 31.7 ± 4.1 mm. Females had smaller diameter than males (30.5 ± 3.7 mm vs 33.3 ± 4.0 mm; p <0.001). Subjects with history of hypertension (n = 11,219; not included in the analysis) had larger mid-ascending aorta diameter compared with normotensive subjects (33.9 ± 3.8 mm vs 31.7 ± 4.1 mm; p < 0.001). Age had the greatest correlation with aortic size (r = 0.55), followed by sex (r = 0.35) and BSA (r = 0.35). Nomograms for predicted mid-ascending aorta diameter were generated at the 95th percentile using quantile regression for subjects without hypertension stratified by age, sex, and BSA. In conclusion, mid-ascending aorta diameter is predominantly associated with sex, age, and BSA. The nomograms established by this study may serve as useful reference values for echocardiographic screening and surveillance.</description><subject>Adults</subject><subject>Age</subject><subject>Anthropometry</subject><subject>Aorta</subject><subject>Aortic valve</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiovascular disease</subject><subject>Connective tissues</subject><subject>Coronary artery disease</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Diastole</subject><subject>Echocardiography</subject><subject>Ethnicity</subject><subject>Females</subject><subject>Heart diseases</subject><subject>Heart rate</subject><subject>Hypertension</subject><subject>Laboratories</subject><subject>Males</subject><subject>Medical records</subject><subject>NMR</subject><subject>Nomograms</subject><subject>Nuclear magnetic resonance</subject><subject>Patients</subject><subject>Regression analysis</subject><subject>Rheumatic heart disease</subject><subject>Sex</subject><subject>Ultrasonic imaging</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkUFv1DAQhS0EosvCTwBZ4sIlYWyvHfuEVm2BSq0qocIRy7GdrqMkXuwEaf89Xu3CgUtPI0uf37x5D6G3BGoCRHzsazP21iRXUyCyBlEDiGdoRWSjKqIIe45WAEArRTbqAr3KuS9PQrh4iS4YQMOllCv085vvfPKT9fiHGRafcRcTvguu2mbrJxemR7yNaTb4KpjRzz5l3B7wQzJTnncxGRssvra7eLQS4mMy-90Bhwlv3TLM-TV60Zkh-zfnuUbfP18_XH6tbu-_3FxubyvLFJsrq7yCznAuqKNCUqKoAeY3RvAWVMO5olRax0C2jdrIVjYdBWc3HZVcMd-wNfpw0t2n-KtcMesxFP_DYCYfl6wpSNYQXiIq6Pv_0D4uaSruNCWEESVF0VwjfqJsijkn3-l9CqNJB01AHwvQvT4XoI8FaBD6pP7urL60o3f_fv1NvACfToAvcfwOPulswzF_F5K3s3YxPLHiD-Pfl9g</recordid><startdate>20180915</startdate><enddate>20180915</enddate><creator>Ayoub, Chadi</creator><creator>Kumar, Gautam</creator><creator>Smith, Carin Y.</creator><creator>Bryant, Sandra C.</creator><creator>Jech, Diane M.</creator><creator>Ionescu, Filip</creator><creator>Petrescu, Ioana</creator><creator>Miller, Fletcher A.</creator><creator>Spittell, Peter C.</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7118-2302</orcidid></search><sort><creationdate>20180915</creationdate><title>Reference Values for Mid-Ascending Aorta Diameters by Transthoracic Echocardiography in Adults</title><author>Ayoub, Chadi ; 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All subjects with transthoracic echocardiograms with mid-ascending aorta diameter measure from January 2004 to December 2009 were identified, and medical records were reviewed for medical history and anthropometric data. Those with aortic valve disease or replacement, congenital heart disease, any connective tissue or inflammatory disease that may affect the aorta, or known aortic aneurysm (>55 mm) were excluded. Mid-ascending aorta diameter was measured in a standardized manner using "leading edge to leading edge" technique at end-diastole. Of 27,839 eligible subjects, 16,620 did not have history of hypertension and were included in the analysis (56.3% female; mean age 52.0 ± 15.8 years), mean mid-ascending aorta diameter 31.7 ± 4.1 mm. Females had smaller diameter than males (30.5 ± 3.7 mm vs 33.3 ± 4.0 mm; p <0.001). Subjects with history of hypertension (n = 11,219; not included in the analysis) had larger mid-ascending aorta diameter compared with normotensive subjects (33.9 ± 3.8 mm vs 31.7 ± 4.1 mm; p < 0.001). Age had the greatest correlation with aortic size (r = 0.55), followed by sex (r = 0.35) and BSA (r = 0.35). Nomograms for predicted mid-ascending aorta diameter were generated at the 95th percentile using quantile regression for subjects without hypertension stratified by age, sex, and BSA. In conclusion, mid-ascending aorta diameter is predominantly associated with sex, age, and BSA. The nomograms established by this study may serve as useful reference values for echocardiographic screening and surveillance.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30075888</pmid><doi>10.1016/j.amjcard.2018.06.006</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-7118-2302</orcidid></addata></record> |
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| subjects | Adults Age Anthropometry Aorta Aortic valve Blood pressure Body mass index Cardiovascular disease Connective tissues Coronary artery disease Coronary vessels Diabetes Diastole Echocardiography Ethnicity Females Heart diseases Heart rate Hypertension Laboratories Males Medical records NMR Nomograms Nuclear magnetic resonance Patients Regression analysis Rheumatic heart disease Sex Ultrasonic imaging |
| title | Reference Values for Mid-Ascending Aorta Diameters by Transthoracic Echocardiography in Adults |
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