Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan

Rationale Exploring differences between mouse strains in drug effects in models of antidepressant-like activity may provide clues to the neurobiology of antidepressant responses. Objectives The objective of this study was to explore whether insensitivity to selective serotonin reuptake inhibitors (S...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Psychopharmacologia 2008-08, Vol.199 (2), p.137-150
Hauptverfasser:	Jacobsen, Jacob P. R., Nielsen, Elsebet Ø., Hummel, Rene, Redrobe, John Paul, Mirza, Naheed, Weikop, Pia
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Hydroxytryptophan - pharmacology 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology Adult and adolescent clinical studies Animals Antidepressants Biological and medical sciences Biomedical and Life Sciences Biomedicine Body Temperature - drug effects Citalopram - pharmacology Depression Dose-Response Relationship, Drug Fluoxetine - analogs & derivatives Fluoxetine - metabolism Genotype Hindlimb Suspension - psychology Hippocampus - drug effects Hippocampus - metabolism Male Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Inbred DBA Microdialysis Mood disorders Motor Activity - drug effects Neuropharmacology Neurosciences Neurotransmitters Norepinephrine Plasma Membrane Transport Proteins - antagonists & inhibitors Norepinephrine Plasma Membrane Transport Proteins - metabolism Pharmacology Pharmacology. Drug treatments Pharmacology/Toxicology Prefrontal Cortex - drug effects Prefrontal Cortex - metabolism Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Review Rodents Serotonin - biosynthesis Serotonin - metabolism Serotonin Receptor Agonists - pharmacology Serotonin Uptake Inhibitors - pharmacology Species Specificity Tyrosine 3-Monooxygenase - biosynthesis Tyrosine 3-Monooxygenase - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!