Hypoxia-inducible factor stabilizers for treating anemia of chronic kidney disease

PURPOSE OF REVIEWSmall-molecule inhibitors of prolyl hydroxylase domain enzymes (PHD inhibitors) are novel renal anemia therapies that increase endogenous erythropoietin (EPO) production by stabilizing hypoxia-inducible factor (HIF). This review summarizes recent findings and future perspectives of...

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Veröffentlicht in:	Current opinion in nephrology and hypertension 2018-09, Vol.27 (5), p.331-338
Hauptverfasser:	Hasegawa, Sho, Tanaka, Tetsuhiro, Nangaku, Masaomi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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