Saponins from European Licorice Roots (Glycyrrhiza glabra)

Saponins from European Licorice Roots (Glycyrrhiza glabra)

European licorice roots (Glycyrrhiza glabra), used in the food and beverage industry due to their distinctive sweet and typical licorice flavor, were fractionated, with the triterpenoid saponins isolated and their chemical structures determined by means of ESIMS, ESIMS/MS, HRESIMS, and 1D/2D NMR exp...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2018-08, Vol.81 (8), p.1734-1744
Hauptverfasser: Schmid, Christian, Dawid, Corinna, Peters, Verena, Hofmann, Thomas
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container_issue 8
container_start_page 1734
container_title Journal of natural products (Washington, D.C.)
container_volume 81
creator Schmid, Christian
Dawid, Corinna
Peters, Verena
Hofmann, Thomas
description European licorice roots (Glycyrrhiza glabra), used in the food and beverage industry due to their distinctive sweet and typical licorice flavor, were fractionated, with the triterpenoid saponins isolated and their chemical structures determined by means of ESIMS, ESIMS/MS, HRESIMS, and 1D/2D NMR experiments. Next to the quantitatively predominant saponin glycyrrhizin (11) and some previously known saponins, the structures of 10 monodesmosidic saponins were assigned unequivocally for the first time, namely, 30-hydroxyglycyrrhizin (1), glycyrrhizin-20-methanoate (2), 24-hydroxyglucoglycyrrhizin (3), rhaoglycyrrhizin (4), 11-deoxorhaoglycyrrhizin (5), rhaoglucoglycyrrhizin (6), rhaogalactoglycyrrhizin (7), 11-deoxo-20α-glycyrrhizin (8), 20α-galacturonoylglycyrrhizin (9), and 20α-rhaoglycyrrhizin (10).
doi_str_mv 10.1021/acs.jnatprod.8b00022
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title Saponins from European Licorice Roots (Glycyrrhiza glabra)
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