Bitter Gourd Suppresses Lipopolysaccharide-Induced Inflammatory Responses

Bitter gourd (Momordica charantia L.) is a popular tropical vegetable in Asian countries. Previously it was shown that bitter gourd placenta extract suppressed lipopolysaccharide (LPS)-induced TNFα production in RAW 264.7 macrophage-like cells. Here it is shown that the butanol-soluble fraction of b...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2008-06, Vol.56 (11), p.4004-4011
Hauptverfasser:	Kobori, Masuko, Nakayama, Hirosuke, Fukushima, Kenji, Ohnishi-Kameyama, Mayumi, Ono, Hiroshi, Fukushima, Tatsunobu, Akimoto, Yukari, Masumoto, Saeko, Yukizaki, Chizuko, Hoshi, Yoshikazu, Deguchi, Tomoaki, Yoshida, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models animal proteins Animals Arthritis, Experimental - chemically induced Arthritis, Experimental - immunology Bioactive Constituents Bitter gourd Butanols Cell Line cell lines Collagen - immunology DNA microarray DNA-binding domains gene expression Gene Expression - drug effects genes gourds inflammation Inflammation - chemically induced Inflammation - prevention & control interleukin-1 linolenoyl-lysophosphatidylcholine linoleoyl-lysophosphatidylcholine Lipopolysaccharides Lysophosphatidylcholines - analysis macrophages Macrophages - physiology MAPKs medicinal properties Mice Mice, Inbred BALB C microarray technology Momordica charantia Momordica charantia - chemistry NFκB Oligonucleotide Array Sequence Analysis plant extracts Plant Extracts - pharmacology RAW 264.7 cells transcription factors tumor necrosis factor-alpha Tumor Necrosis Factor-alpha - biosynthesis Tumor Necrosis Factor-alpha - genetics
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