Mkp-1 cross-talks with Nrf2/Ho-1 pathway protecting against intestinal inflammation

Inflammatory bowel disease (IBD) is associated with intense oxidative stress, contributes to colonic damage and tumorigenesis. Mitogen-activated protein kinase phosphatase 1 (Mkp-1) is an essential negative regulator of the innate immune response. However, its role in colitis, and its association wi...

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Veröffentlicht in:Free radical biology & medicine 2018-08, Vol.124, p.541-549
Hauptverfasser: Li, Jing, Wang, Hongyan, Zheng, Zhaohong, Luo, Lin, Wang, Peng, Liu, Kaihua, Namani, Akhileshwar, Jiang, Zhinong, Wang, Xiu Jun, Tang, Xiuwen
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Sprache:eng
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