Impairment of regulatory T cells in patients with neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) is a life-threatening condition that can occur in about 7% of pre-term infants, and approximately 20% to 30% of the cases will end in death. An overactive immune response is thought to be a primary instigator of many symptoms during NEC. Hence, we hypothesized that NE...

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Veröffentlicht in:	International immunopharmacology 2018-10, Vol.63, p.19-25
Hauptverfasser:	Pang, Yin, Du, Xiaoya, Xu, Xueli, Wang, Mengjie, Li, Zhichang
Format:	Artikel
Sprache:	eng
Schlagworte:	CD223 antigen CD25 antigen CD3 antigen CD4 antigen Cell proliferation Cells CTLA-4 protein Enterocolitis Enterocolitis, Necrotizing - immunology Female Humans Immune response Immune system Immunoregulation Impairment Infant mortality Infant, Newborn Infant, Newborn, Diseases - immunology Infants Inflammatory diseases Interleukin 10 Interleukin 17 Leukocytes (mononuclear) Lymphocytes Lymphocytes T Male Necrotizing enterocolitis Neonates Patients Peripheral blood mononuclear cells Premature birth Premature infant Regulatory T cell T-Lymphocytes, Regulatory - immunology Weight
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