Inactivating NADH:quinone oxidoreductases affects the growth and metabolism of Klebsiella pneumoniae

NADH:quinone oxidoreductases (NQOs) act as the electron entry sites in bacterial respiration and oxidize intracellular NADH that is essential for the synthesis of numerous molecules. Klebsiella pneumoniae contains three NQOs (NDH‐1, NDH‐2, and NQR). The effects of inactivating these NQOs, separately...

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Veröffentlicht in:	Biotechnology and applied biochemistry 2018-11, Vol.65 (6), p.857-864
Hauptverfasser:	Zhang, Lijuan, Bao, Wenjing, Wei, Renquan, Fu, Shuilin, Gong, Heng
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3‐propanediol 2,3‐butanediol Aerobic conditions Biosynthesis Butanediol Cell culture Chains Chemical synthesis Deficient mutant Electron transport Glycerol Intracellular intracellular redox Klebsiella Klebsiella pneumoniae Metabolic engineering Metabolism Mutants NAD NADH NADH:quinone oxidoreductase Nicotinamide adenine dinucleotide Quinones
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