HER2 status in patients with residual rectal cancer after preoperative chemoradiotherapy: the relationship with molecular results and clinicopathologic features

The specific role of human epidermal growth factor receptor-2 ( HER2 ) status in rectal cancers remains unclear. This study therefore aimed to explore clinicopathologic and molecular characteristics, and prognostic value of HER2 -positivity in residual mid- and/or low-rectal cancers after preoperati...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2018-10, Vol.473 (4), p.413-423
Hauptverfasser:	Park, Jun Seok, Yoon, Ghilsuk, Kim, Hye Jin, Park, Soo Yeun, Choi, Gyu Seog, Kang, Min Kyu, Kim, Jong Gwang, Jang, Jung-Sik, Seo, An Na
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Cancer Chemoradiotherapy Chemotherapy Colorectal cancer Epidermal growth factor ErbB-2 protein Gene amplification Gene expression Health risk assessment Immunohistochemistry K-Ras protein Medical prognosis Medicine Medicine & Public Health Microsatellite instability Mutation Original Article Pathology Patients Polymerase chain reaction Proteins Radiation therapy Rectum Stability Stability analysis Survival
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