Selective alpha 7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

AZD0328, a novel spirofuropyridine neuronal nicotinic receptor partial agonist, was used to investigate the role of alpha 7 neuronal nicotinic receptor (NNR) activation in the modulation of midbrain dopamine neuron function, cortical dopamine release and on two behavioral tasks known to be dependent...

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Veröffentlicht in:	Biochemical pharmacology 2009-10, Vol.78 (7), p.880-888
Hauptverfasser:	Sydserff, Simon, Sutton, E J, Song, Dekun, Quirk, Michael C, Maciag, Carla, Li, Chaoying, Jonak, Gerald, Gurley, David, Gordon, John C, Christian, Edward P, Doherty, James J, Hudzik, Tom, Johnson, Edwin, Mrzljak, Ladislav, Piser, Tim, Smagin, Gennady N, Wang, Yi, Widzowski, Dan, Smith, Jeffrey S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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