The ATP-gated P2X sub(1) Receptor Plays a Pivotal Role in Activation of Aspirin-treated Platelets by Thrombin and Epinephrine

Human platelets express protease-activated receptor 1 (PAR1) and PAR4 but limited data indicate for differences in signal transduction. We studied the involvement of PAR1 and PAR4 in the cross-talk between thrombin and epinephrine. The results show that epinephrine acted via alpha sub(2A)-adrenergic...

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Veröffentlicht in:	The Journal of biological chemistry 2008-07, Vol.283 (27), p.18493-18504
Hauptverfasser:	Grenegaard, Magnus, Vretenbrant-Oeberg, Karin, Nylander, Martina, Desilets, Stephanie, Lindstroem, Eva G, Larsson, Anders, Ramstroem, Ida, Ramstroem, Sofia, Lindahl, Tomas L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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