Selenium-containing compounds attenuate peroxynitrite-mediated NF-κB and AP-1 activation and interleukin-8 gene and protein expression in human leukocytes

A growing body of evidence indicates that the powerful oxidant peroxynitrite (ONOO −) may function as an intracellular signal for production of proinflammatory cytokines, such as interleukin-8 (IL-8) in human leukocytes. In this study, we investigated whether selenomethionine, selenocysteine, and th...

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Veröffentlicht in:	Free radical biology & medicine 2003-11, Vol.35 (9), p.1018-1027
Hauptverfasser:	József, Levente, Filep, János G
Format:	Artikel
Sprache:	eng
Schlagworte:	AP-1 Ebselen Free radicals Inflammation Interleukin-8 gene expression Leukocytes NF-κB Peroxynitrite Selenocysteine Selenomethionine
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