Membrane Reconstitution of Monoamine Oxidase Enzymes on Supported Lipid Bilayers

Monoamine oxidase A and B (MAO-A and B) are mitochondrial outer membrane enzymes that are implicated in a number of human diseases, and the pharmacological inhibition of these enzymes is a promising therapeutic strategy to alleviate disease symptoms. It has been suggested that optimal levels of enzy...

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Veröffentlicht in:	Langmuir 2018-09, Vol.34 (36), p.10764-10773
Hauptverfasser:	Wang, Liulin, Biswas, Kabir H, Yoon, Bo Kyeong, Kawakami, Lisa M, Park, Soohyun, Groves, Jay T, Li, Lin, Huang, Wei, Cho, Nam-Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Clorgyline - chemistry Indans - chemistry Lipid Bilayers - chemistry Lipid Bilayers - metabolism Monoamine Oxidase - metabolism Monoamine Oxidase Inhibitors - chemistry Phosphatidylcholines - chemistry Phosphatidylcholines - metabolism Phosphatidylserines - chemistry Phosphatidylserines - metabolism Protein Binding Quartz Crystal Microbalance Techniques Static Electricity
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