A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets
Purpose Essential fatty acids are critical for brain growth and neurodevelopment in infancy. Maternal diet and supplement use have a significant impact on the fat composition of human milk. The objective of this study is to assess supplement utilization patterns and fatty acid and brain-derived neur...
Gespeichert in:
| Veröffentlicht in: | European journal of nutrition 2019-09, Vol.58 (6), p.2401-2410 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2410 |
|---|---|
| container_issue | 6 |
| container_start_page | 2401 |
| container_title | European journal of nutrition |
| container_volume | 58 |
| creator | Perrin, Maryanne T. Pawlak, Roman Dean, Lisa L. Christis, Amber Friend, Linda |
| description | Purpose
Essential fatty acids are critical for brain growth and neurodevelopment in infancy. Maternal diet and supplement use have a significant impact on the fat composition of human milk. The objective of this study is to assess supplement utilization patterns and fatty acid and brain-derived neurotrophic factor (BDNF) concentrations in the breast milk of women following vegan, vegetarian, and omnivore diet patterns.
Methods
This is a cross-sectional, observational study of 74 lactating women in the United States following a vegan (
n
= 26), vegetarian (
n
= 22), or omnivore (
n
= 26) diet pattern. A single breast milk sample was collected from each participant and assessed for fatty acids and BDNF.
Results
Median unsaturated fatty acids in the breast milk of vegan, vegetarian, and omnivores, as a percentage of total fatty acids, was 66.0, 57.8, and 56.2%, respectively (
p
|
| doi_str_mv | 10.1007/s00394-018-1793-z |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2078579990</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2078579990</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-854fa6038bcb1fb285f193cd49ec475bfe4343ef920e8c4355cbc11bac54dc0e3</originalsourceid><addsrcrecordid>eNp1kcFu1DAQhiMEoqXwAFyQJS5FImDHdhIfS2lppQoucLYce7x1SezFdrbaPlCfE6fbFgmpp5nRfPOP9P9V9ZbgTwTj7nPCmApWY9LXpBO0vnlW7RNG27ptCH_-2ONur3qV0hXGuKEteVntUYw5IR3er26PkI4hpTqBzi54NaKUZ7NFwSKrct4ipZ1JSHmDhqicrw1EtwGDPMwx5BjWl04XVOcQ0eGXr99PPyDn0eU8KY8mN_5GNoYJjQVQ2fkVug4TeGTDOIbrZd7ASvmPS4Gsolv65VmYvNuECMg4yOl19cKqMcGb-3pQ_To9-Xl8Vl_8-HZ-fHRRa0Z4rnvOrGox7Qc9EDs0PbdEUG2YAM06PlhglFGwosHQa0Y514MmZFCaM6Mx0IPqcKe7juHPDCnLySUN46g8hDnJ4mXPOyEELuj7_9CrMMdi4B3VctH2TBSK7Kg7lyNYuY5uUnErCZZLiHIXoiwhyiVEeVNu3t0rz8ME5vHiIbUCNDsglZVfQfz3-mnVvz_oqmw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2076596849</pqid></control><display><type>article</type><title>A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Perrin, Maryanne T. ; Pawlak, Roman ; Dean, Lisa L. ; Christis, Amber ; Friend, Linda</creator><creatorcontrib>Perrin, Maryanne T. ; Pawlak, Roman ; Dean, Lisa L. ; Christis, Amber ; Friend, Linda</creatorcontrib><description>Purpose
Essential fatty acids are critical for brain growth and neurodevelopment in infancy. Maternal diet and supplement use have a significant impact on the fat composition of human milk. The objective of this study is to assess supplement utilization patterns and fatty acid and brain-derived neurotrophic factor (BDNF) concentrations in the breast milk of women following vegan, vegetarian, and omnivore diet patterns.
Methods
This is a cross-sectional, observational study of 74 lactating women in the United States following a vegan (
n
= 26), vegetarian (
n
= 22), or omnivore (
n
= 26) diet pattern. A single breast milk sample was collected from each participant and assessed for fatty acids and BDNF.
Results
Median unsaturated fatty acids in the breast milk of vegan, vegetarian, and omnivores, as a percentage of total fatty acids, was 66.0, 57.8, and 56.2%, respectively (
p
< 0.001). Total omega-3 percentages were 2.29% for vegans, 1.55% for vegetarians, and 1.46% for omnivores (
p
< 0.001). Docosahexaenoic acid percentages were not different by diet pattern, but over 80% of participants had milk concentrations below 0.30% of total fatty acids. Reports of omega-3 supplements use (10/74) and weekly seafood consumption (3/74) were limited. BDNF was not detectable in any samples.
Conclusions
Breast milk from vegans had significantly higher unsaturated fat and total omega-3 fats, and lower saturated fats,
trans
fats, and omega-6 to omega-3 ratios than their vegetarian and omnivore counterparts. Docosahexaenoic acid concentrations in breast milk were low regardless of maternal diet pattern, and were reflective of low seafood intake and supplement use.</description><identifier>ISSN: 1436-6207</identifier><identifier>EISSN: 1436-6215</identifier><identifier>DOI: 10.1007/s00394-018-1793-z</identifier><identifier>PMID: 30051170</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adult ; Baby foods ; Brain-derived neurotrophic factor ; Brain-Derived Neurotrophic Factor - metabolism ; Breast milk ; Breastfeeding & lactation ; Chemistry ; Chemistry and Materials Science ; Cross-Sectional Studies ; Diet ; Diet - methods ; Diet, Vegan - methods ; Diet, Vegetarian - methods ; Dietary supplements ; Docosahexaenoic acid ; Fatty acids ; Fatty Acids, Essential - metabolism ; Female ; Humans ; Lactation ; Milk, Human - metabolism ; Nutrient deficiency ; Nutrition ; Original Contribution ; Seafood ; Vegetarian diet ; Vegetarianism ; Womens health</subject><ispartof>European journal of nutrition, 2019-09, Vol.58 (6), p.2401-2410</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>European Journal of Nutrition is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-854fa6038bcb1fb285f193cd49ec475bfe4343ef920e8c4355cbc11bac54dc0e3</citedby><cites>FETCH-LOGICAL-c415t-854fa6038bcb1fb285f193cd49ec475bfe4343ef920e8c4355cbc11bac54dc0e3</cites><orcidid>0000-0001-6839-5422 ; 0000-0002-2407-9548 ; 0000-0002-1645-8310</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00394-018-1793-z$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00394-018-1793-z$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30051170$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Perrin, Maryanne T.</creatorcontrib><creatorcontrib>Pawlak, Roman</creatorcontrib><creatorcontrib>Dean, Lisa L.</creatorcontrib><creatorcontrib>Christis, Amber</creatorcontrib><creatorcontrib>Friend, Linda</creatorcontrib><title>A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets</title><title>European journal of nutrition</title><addtitle>Eur J Nutr</addtitle><addtitle>Eur J Nutr</addtitle><description>Purpose
Essential fatty acids are critical for brain growth and neurodevelopment in infancy. Maternal diet and supplement use have a significant impact on the fat composition of human milk. The objective of this study is to assess supplement utilization patterns and fatty acid and brain-derived neurotrophic factor (BDNF) concentrations in the breast milk of women following vegan, vegetarian, and omnivore diet patterns.
Methods
This is a cross-sectional, observational study of 74 lactating women in the United States following a vegan (
n
= 26), vegetarian (
n
= 22), or omnivore (
n
= 26) diet pattern. A single breast milk sample was collected from each participant and assessed for fatty acids and BDNF.
Results
Median unsaturated fatty acids in the breast milk of vegan, vegetarian, and omnivores, as a percentage of total fatty acids, was 66.0, 57.8, and 56.2%, respectively (
p
< 0.001). Total omega-3 percentages were 2.29% for vegans, 1.55% for vegetarians, and 1.46% for omnivores (
p
< 0.001). Docosahexaenoic acid percentages were not different by diet pattern, but over 80% of participants had milk concentrations below 0.30% of total fatty acids. Reports of omega-3 supplements use (10/74) and weekly seafood consumption (3/74) were limited. BDNF was not detectable in any samples.
Conclusions
Breast milk from vegans had significantly higher unsaturated fat and total omega-3 fats, and lower saturated fats,
trans
fats, and omega-6 to omega-3 ratios than their vegetarian and omnivore counterparts. Docosahexaenoic acid concentrations in breast milk were low regardless of maternal diet pattern, and were reflective of low seafood intake and supplement use.</description><subject>Adult</subject><subject>Baby foods</subject><subject>Brain-derived neurotrophic factor</subject><subject>Brain-Derived Neurotrophic Factor - metabolism</subject><subject>Breast milk</subject><subject>Breastfeeding & lactation</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Cross-Sectional Studies</subject><subject>Diet</subject><subject>Diet - methods</subject><subject>Diet, Vegan - methods</subject><subject>Diet, Vegetarian - methods</subject><subject>Dietary supplements</subject><subject>Docosahexaenoic acid</subject><subject>Fatty acids</subject><subject>Fatty Acids, Essential - metabolism</subject><subject>Female</subject><subject>Humans</subject><subject>Lactation</subject><subject>Milk, Human - metabolism</subject><subject>Nutrient deficiency</subject><subject>Nutrition</subject><subject>Original Contribution</subject><subject>Seafood</subject><subject>Vegetarian diet</subject><subject>Vegetarianism</subject><subject>Womens health</subject><issn>1436-6207</issn><issn>1436-6215</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kcFu1DAQhiMEoqXwAFyQJS5FImDHdhIfS2lppQoucLYce7x1SezFdrbaPlCfE6fbFgmpp5nRfPOP9P9V9ZbgTwTj7nPCmApWY9LXpBO0vnlW7RNG27ptCH_-2ONur3qV0hXGuKEteVntUYw5IR3er26PkI4hpTqBzi54NaKUZ7NFwSKrct4ipZ1JSHmDhqicrw1EtwGDPMwx5BjWl04XVOcQ0eGXr99PPyDn0eU8KY8mN_5GNoYJjQVQ2fkVug4TeGTDOIbrZd7ASvmPS4Gsolv65VmYvNuECMg4yOl19cKqMcGb-3pQ_To9-Xl8Vl_8-HZ-fHRRa0Z4rnvOrGox7Qc9EDs0PbdEUG2YAM06PlhglFGwosHQa0Y514MmZFCaM6Mx0IPqcKe7juHPDCnLySUN46g8hDnJ4mXPOyEELuj7_9CrMMdi4B3VctH2TBSK7Kg7lyNYuY5uUnErCZZLiHIXoiwhyiVEeVNu3t0rz8ME5vHiIbUCNDsglZVfQfz3-mnVvz_oqmw</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Perrin, Maryanne T.</creator><creator>Pawlak, Roman</creator><creator>Dean, Lisa L.</creator><creator>Christis, Amber</creator><creator>Friend, Linda</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6839-5422</orcidid><orcidid>https://orcid.org/0000-0002-2407-9548</orcidid><orcidid>https://orcid.org/0000-0002-1645-8310</orcidid></search><sort><creationdate>20190901</creationdate><title>A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets</title><author>Perrin, Maryanne T. ; Pawlak, Roman ; Dean, Lisa L. ; Christis, Amber ; Friend, Linda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-854fa6038bcb1fb285f193cd49ec475bfe4343ef920e8c4355cbc11bac54dc0e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Baby foods</topic><topic>Brain-derived neurotrophic factor</topic><topic>Brain-Derived Neurotrophic Factor - metabolism</topic><topic>Breast milk</topic><topic>Breastfeeding & lactation</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Cross-Sectional Studies</topic><topic>Diet</topic><topic>Diet - methods</topic><topic>Diet, Vegan - methods</topic><topic>Diet, Vegetarian - methods</topic><topic>Dietary supplements</topic><topic>Docosahexaenoic acid</topic><topic>Fatty acids</topic><topic>Fatty Acids, Essential - metabolism</topic><topic>Female</topic><topic>Humans</topic><topic>Lactation</topic><topic>Milk, Human - metabolism</topic><topic>Nutrient deficiency</topic><topic>Nutrition</topic><topic>Original Contribution</topic><topic>Seafood</topic><topic>Vegetarian diet</topic><topic>Vegetarianism</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Perrin, Maryanne T.</creatorcontrib><creatorcontrib>Pawlak, Roman</creatorcontrib><creatorcontrib>Dean, Lisa L.</creatorcontrib><creatorcontrib>Christis, Amber</creatorcontrib><creatorcontrib>Friend, Linda</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Career & Technical Education Database</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Perrin, Maryanne T.</au><au>Pawlak, Roman</au><au>Dean, Lisa L.</au><au>Christis, Amber</au><au>Friend, Linda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets</atitle><jtitle>European journal of nutrition</jtitle><stitle>Eur J Nutr</stitle><addtitle>Eur J Nutr</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>58</volume><issue>6</issue><spage>2401</spage><epage>2410</epage><pages>2401-2410</pages><issn>1436-6207</issn><eissn>1436-6215</eissn><abstract>Purpose
Essential fatty acids are critical for brain growth and neurodevelopment in infancy. Maternal diet and supplement use have a significant impact on the fat composition of human milk. The objective of this study is to assess supplement utilization patterns and fatty acid and brain-derived neurotrophic factor (BDNF) concentrations in the breast milk of women following vegan, vegetarian, and omnivore diet patterns.
Methods
This is a cross-sectional, observational study of 74 lactating women in the United States following a vegan (
n
= 26), vegetarian (
n
= 22), or omnivore (
n
= 26) diet pattern. A single breast milk sample was collected from each participant and assessed for fatty acids and BDNF.
Results
Median unsaturated fatty acids in the breast milk of vegan, vegetarian, and omnivores, as a percentage of total fatty acids, was 66.0, 57.8, and 56.2%, respectively (
p
< 0.001). Total omega-3 percentages were 2.29% for vegans, 1.55% for vegetarians, and 1.46% for omnivores (
p
< 0.001). Docosahexaenoic acid percentages were not different by diet pattern, but over 80% of participants had milk concentrations below 0.30% of total fatty acids. Reports of omega-3 supplements use (10/74) and weekly seafood consumption (3/74) were limited. BDNF was not detectable in any samples.
Conclusions
Breast milk from vegans had significantly higher unsaturated fat and total omega-3 fats, and lower saturated fats,
trans
fats, and omega-6 to omega-3 ratios than their vegetarian and omnivore counterparts. Docosahexaenoic acid concentrations in breast milk were low regardless of maternal diet pattern, and were reflective of low seafood intake and supplement use.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>30051170</pmid><doi>10.1007/s00394-018-1793-z</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-6839-5422</orcidid><orcidid>https://orcid.org/0000-0002-2407-9548</orcidid><orcidid>https://orcid.org/0000-0002-1645-8310</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1436-6207 |
| ispartof | European journal of nutrition, 2019-09, Vol.58 (6), p.2401-2410 |
| issn | 1436-6207 1436-6215 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2078579990 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Baby foods Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Breast milk Breastfeeding & lactation Chemistry Chemistry and Materials Science Cross-Sectional Studies Diet Diet - methods Diet, Vegan - methods Diet, Vegetarian - methods Dietary supplements Docosahexaenoic acid Fatty acids Fatty Acids, Essential - metabolism Female Humans Lactation Milk, Human - metabolism Nutrient deficiency Nutrition Original Contribution Seafood Vegetarian diet Vegetarianism Womens health |
| title | A cross-sectional study of fatty acids and brain-derived neurotrophic factor (BDNF) in human milk from lactating women following vegan, vegetarian, and omnivore diets |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T12%3A02%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20cross-sectional%20study%20of%20fatty%20acids%20and%20brain-derived%20neurotrophic%20factor%20(BDNF)%20in%20human%20milk%20from%20lactating%20women%20following%20vegan,%20vegetarian,%20and%20omnivore%20diets&rft.jtitle=European%20journal%20of%20nutrition&rft.au=Perrin,%20Maryanne%20T.&rft.date=2019-09-01&rft.volume=58&rft.issue=6&rft.spage=2401&rft.epage=2410&rft.pages=2401-2410&rft.issn=1436-6207&rft.eissn=1436-6215&rft_id=info:doi/10.1007/s00394-018-1793-z&rft_dat=%3Cproquest_cross%3E2078579990%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2076596849&rft_id=info:pmid/30051170&rfr_iscdi=true |