Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from A beta 40

The 2D IR spectra of the amide-I vibrations of amyloid fibrils from A beta 40 were obtained. The matured fibrils formed from strands having isotopic substitution by super(13)CFormula super(18)O at Gly-38, Gly-33, Gly-29, or Ala-21 show vibrational exciton spectra having reduced dimensionality. Indee...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2008-06, Vol.105 (22), p.7720-7725
Hauptverfasser: Kim, Yung Sam, Liu, Liu, Axelsen, Paul H, Hochstrasser, Robin M
Format: Artikel
Sprache:eng
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