Phase 2 trial of two courses of cyclophosphamide and etoposide for relapsed high‐risk osteosarcoma patients

BACKGROUND: A phase 2 trial was carried out to assess the antineoplastic activity of 2 courses of cyclophosphamide‐etoposide in relapsed osteosarcoma patients. METHODS: Twenty‐six relapsed osteosarcoma patients with a median age of 18.5 years (8.3‐47.1) were enrolled. Seven patients were in first re...

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Veröffentlicht in:	Cancer 2009-07, Vol.115 (13), p.2980-2987
Hauptverfasser:	Massimo, Berger, Giovanni, Grignani, Stefano, Ferrari, Eleonora, Biasin, Adalberto, Brach del Prever, Sandra, Aliberti, Francesco, Saglio, Massimo, Aglietta, Franca, Fagioli
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bone Neoplasms - drug therapy Child cyclophosphamide Cyclophosphamide - administration & dosage Disease-Free Survival Diseases of the osteoarticular system etoposide Etoposide - administration & dosage Female Hematopoietic Stem Cell Mobilization Humans Male Medical sciences Middle Aged Neoplasm Metastasis Neoplasm Recurrence, Local - drug therapy Osteosarcoma - drug therapy osteosarcoma relapse Tumors Tumors of striated muscle and skeleton
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