Estimating mean local posterior predictive benefit for biomarker-guided treatment strategies

Precision medicine has emerged from the awareness that many human diseases are intrinsically heterogeneous with respect to their pathogenesis and composition among patients as well as dynamic over the course therapy. Its successful application relies on our understanding of distinct molecular profil...

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Veröffentlicht in:	Statistical methods in medical research 2019-09, Vol.28 (9), p.2820-2833
Hauptverfasser:	Huang, Meilin, Hobbs, Brian P
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological markers Biomarkers Estimation Glioma Medical prognosis Medicine Paradigms Pathogenesis Population statistics Precision medicine Simulation Treatment methods
Online-Zugang:	Volltext
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