Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFκB transcription factors

Malignant gliomas are a debilitating class of brain tumors that are resistant to radiation and chemotherapeutic drugs, contributing to the poor prognosis associated with these tumors. Over-expression of transcription factors such as NFκB and AP-1 contribute to the enhanced glioma survival, radioresi...

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Veröffentlicht in:	Journal of neurochemistry 2007-07, Vol.102 (2), p.522-538
Hauptverfasser:	Dhandapani, Krishnan M, Mahesh, Virendra B, Brann, Darrell W
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt AP-1 astrocyte Biological and medical sciences chemotherapy c‐Jun N‐terminal kinase Fundamental and applied biological sciences. Psychology glioma Medical sciences mitogen-activated protein kinase Molecular and cellular biology Molecular genetics Neurology NFκB radiation Transcription. Transcription factor. Splicing. Rna processing Tumors of the nervous system. Phacomatoses
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