Intravascular hemolysis following low dose daily rifampin

We report two pediatric patients with rifampin‐induced hemolysis following treatment with low daily dose rifampin for methicillin‐resistant Staphylococcus aureus (MRSA). With the increased use of rifampin to treat MRSA, physicians should be aware that patients receiving rifampin therapy are at risk...

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Veröffentlicht in:	Pediatric Blood & Cancer 2008-12, Vol.51 (6), p.821-823
Hauptverfasser:	Neunert, Cindy E., Paranjape, Geeta S., Cameron, Scott, Rogers, Zora R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent anemia Anemia, Hemolytic - etiology Antibiotics, Antitubercular - administration & dosage Antibiotics, Antitubercular - adverse effects Drug Therapy, Combination Female hemolysis Hemolysis - drug effects Humans Infant Male Methicillin Resistance Methicillin-Resistant Staphylococcus aureus - drug effects rifampin Rifampin - administration & dosage Rifampin - adverse effects Staphylococcal Infections - drug therapy Staphylococcus aureus
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Zusammenfassung:	We report two pediatric patients with rifampin‐induced hemolysis following treatment with low daily dose rifampin for methicillin‐resistant Staphylococcus aureus (MRSA). With the increased use of rifampin to treat MRSA, physicians should be aware that patients receiving rifampin therapy are at risk for hemolysis, even at low daily doses. Pediatr Blood Cancer 2008;51:821–823. © 2008 Wiley‐Liss, Inc.
ISSN:	1545-5009 1545-5017 1096-911X
DOI:	10.1002/pbc.21709