PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: expression patterns and clinical implications

Undifferentiated carcinoma with osteoclast-like giant cells (UCOGC), a variant of pancreatic ductal adenocarcinoma (PDAC), has a striking genetic similarity to PDAC but a significantly improved overall survival. We hypothesize that this difference could be due to the immune response to the tumor, an...

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Veröffentlicht in:	Human pathology 2018-11, Vol.81, p.157-165
Hauptverfasser:	Luchini, Claudio, Cros, Jerome, Pea, Antonio, Pilati, Camilla, Veronese, Nicola, Rusev, Borislav, Capelli, Paola, Mafficini, Andrea, Nottegar, Alessia, Brosens, Lodewijk A.A., Noë, Michaël, Offerhaus, G. Johan A., Chianchiano, Peter, Riva, Giulio, Piccoli, Paola, Parolini, Claudia, Malleo, Giuseppe, Lawlor, Rita T., Corbo, Vincenzo, Sperandio, Nicola, Barbareschi, Mattia, Fassan, Matteo, Cheng, Liang, Wood, Laura D., Scarpa, Aldo
Format:	Artikel
Sprache:	eng
Schlagworte:	Archives & records Lymphocytes Mutation Osteoclast Pancreatic cancer Pathology PDAC Tumor-associated macrophages UCOGC
Online-Zugang:	Volltext
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