Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring

[Display omitted] The use of DNA aptamers in biosensors for the quantification of pharmaceuticals in the clinics would help to overcome the limitations of antibody-based detection for small molecules. The interest for such systems is proven by the ever-increasing number of aptamer-based solutions fo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2018-09, Vol.159, p.341-347
Hauptverfasser:	Tenaglia, Enrico, Ferretti, Anna, Decosterd, Laurent A., Werner, Dominique, Mercier, Thomas, Widmer, Nicolas, Buclin, Thierry, Guiducci, Carlotta
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - blood Aptamers, Nucleotide - blood DNA aptamers Drug dosage Drug monitoring Drug Monitoring - methods Drug Monitoring - standards Humans Label-free biosensors SPR Surface Plasmon Resonance Tobramycin Tobramycin - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!