Claudin-4 Expression Is Associated With Disease-Free Survival in Breast Carcinoma-in-Situ: Mean Follow-up of 8.2 Years

Claudin-4 expression in carcinoma-in-situ (CIS) is unknown. In 86 patients with pure CIS and mean follow-up of 8.2 years, claudin-4-high expression was more frequent than claudin-4-low. However, claudin-4-low was associated with worse disease-free survival than claudin-4-high. Claudins are tight jun...

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Veröffentlicht in:	Clinical breast cancer 2018-10, Vol.18 (5), p.e1111-e1116
Hauptverfasser:	Duarte, Giuliano M., Almeida, Natalie Rios, Tocchet, Fernando, Espinola, Juliana, Barreto, Carolina Teixeira de Resende, Pinto, Glauce Aparecida, Soares, Fernando Augusto, Marshall, Priscila, Russano de Paiva Silva, Geisilene
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers, Tumor - analysis Breast carcinoma Breast Carcinoma In Situ - metabolism Breast Carcinoma In Situ - mortality Breast Carcinoma In Situ - pathology Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Carcinoma in situ Claudin Claudin-4 - biosynthesis Cohort Studies Disease-Free Survival Female Humans Kaplan-Meier Estimate Middle Aged Retrospective Studies Survival Tissue microarray
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