From Traumatic Childhood to Cocaine Abuse: The Critical Function of the Immune System

Experiencing traumatic childhood is a risk factor for developing substance use disorder, but the mechanisms that underlie this relationship have not been determined. Adverse childhood experiences affect the immune system, and the immune system mediates the effects of psychostimulants. However, wheth...

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Veröffentlicht in:	Biological psychiatry (1969) 2018-12, Vol.84 (12), p.905-916
Hauptverfasser:	Lo Iacono, Luisa, Catale, Clarissa, Martini, Alessandro, Valzania, Alessandro, Viscomi, Maria Teresa, Chiurchiù, Valerio, Guatteo, Ezia, Bussone, Silvia, Perrone, Fabiana, Di Sabato, Paola, Aricò, Eleonora, D’Argenio, Alberto, Troisi, Alfonso, Mercuri, Nicola B., Maccarrone, Mauro, Puglisi-Allegra, Stefano, Casella, Pietro, Carola, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	Childhood maltreatment Cocaine Dopamine GW2580 Microglia Minocycline Stress Toll-like receptor 4 Ventral tegmental area
Online-Zugang:	Volltext
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