Antibacterial Mimics of Natural Products by Side-Chain Functionalization of Bicyclic Tetramic Acids

Tetramic acids with unsaturated acyl chains are widely found in natural products possessing a range of biological activities, and bicyclic tetramates represent a suitable scaffold to prepare simple mimics of such complex molecules. An efficient route to functionalize the C(6)-acyl group of a bicycli...

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Veröffentlicht in:Journal of organic chemistry 2018-09, Vol.83 (17), p.10303-10317
Hauptverfasser: Josa-Culleré, Laia, Pretsch, Alexander, Pretsch, Dagmar, Moloney, Mark G
Format: Artikel
Sprache:eng
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