Curcumin for malaria therapy

Malaria remains a major global health concern. New, inexpensive, and effective antimalarial agents are urgently needed. Here we show that curcumin, a polyphenolic organic molecule derived from turmeric, inhibits chloroquine-resistant Plasmodium falciparum growth in culture in a dose dependent manner...

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Veröffentlicht in:	Biochemical and biophysical research communications 2005-01, Vol.326 (2), p.472-474
Hauptverfasser:	Reddy, Raju C., Vatsala, Palakkodu G., Keshamouni, Venkateshwar G., Padmanaban, Govindarajan, Rangarajan, Pundi N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimalarials - administration & dosage Antimalarials - pharmacology Antimalarials - therapeutic use Artemisinin Curcuma longa Curcumin Curcumin - administration & dosage Curcumin - pharmacology Curcumin - therapeutic use Inhibitory Concentration 50 Malaria Malaria - blood Malaria - drug therapy Malaria - parasitology Male Mice Parasitemia - blood Parasitemia - drug therapy Parasitemia - parasitology Plasmodium Plasmodium berghei Plasmodium berghei - drug effects Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - growth & development Survival Rate
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