Study of new sheep bone and Zn/Ca ratio around TiAlV screw: PIXE–RBS analysis

This study reports on in vivo particle induced X-ray emission (PIXE) measurements combined with Rutherford backscattering spectroscopy (RBS) analyses of new remodeled sheep bone formed around TiAlV screws. The implants (screws) were anodized by a modified TiMax™ process. The interface between the im...

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Veröffentlicht in:Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms Beam interactions with materials and atoms, 2008-03, Vol.266 (5), p.813-819
Hauptverfasser: Guibert, G., Munnik, F., Langhoff, J.D., Von Rechenberg, B., Buffat, Ph.A., Laub, D., Faber, L., Ducret, F., Gerber, I., Mikhailov, S.
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container_issue 5
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container_title Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms
container_volume 266
creator Guibert, G.
Munnik, F.
Langhoff, J.D.
Von Rechenberg, B.
Buffat, Ph.A.
Laub, D.
Faber, L.
Ducret, F.
Gerber, I.
Mikhailov, S.
description This study reports on in vivo particle induced X-ray emission (PIXE) measurements combined with Rutherford backscattering spectroscopy (RBS) analyses of new remodeled sheep bone formed around TiAlV screws. The implants (screws) were anodized by a modified TiMax™ process. The interface between the implant and the bone was carefully investigated. [Zn]/[Ca] in-depth composition profiles as well as Ca, Fe elemental maps were recorded. The thickness of new bone formed around the screw reached 300–400μm. Osteon and Osteoid phases were identified in the new bone. A higher [Zn]/[Ca] ratio was observed in the new bone as compared to the mature bone. Blood vessels were observed in the bone in close contact with the screw. This study shows the potential of ion beam analysis for biological and biomedical characterization.
doi_str_mv 10.1016/j.nimb.2008.01.025
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subjects Biomaterials
New bone
PIXE–RBS method
title Study of new sheep bone and Zn/Ca ratio around TiAlV screw: PIXE–RBS analysis
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