Iris melanoma presenting as childhood glaucoma

Iris melanoma presenting as childhood glaucoma

PURPOSETo describe the natural history and management of a rare case of iris melanoma in a pediatric patient. OBSERVATIONSA Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly elevated intraocular pressure with advanced optic nerve c...

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Veröffentlicht in:American journal of ophthalmology case reports 2018, Vol.11, p.56-60
Hauptverfasser: Gapsis, Briana C, Warren, Nichelle A, Nutaitis, Matthew J, Bonaparte, Leah A, Cooper, Samuel L, Ashenafi, Michael, Grossniklaus, Hans E, Magrath, George N
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container_title American journal of ophthalmology case reports
container_volume 11
creator Gapsis, Briana C
Warren, Nichelle A
Nutaitis, Matthew J
Bonaparte, Leah A
Cooper, Samuel L
Ashenafi, Michael
Grossniklaus, Hans E
Magrath, George N
description PURPOSETo describe the natural history and management of a rare case of iris melanoma in a pediatric patient. OBSERVATIONSA Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly elevated intraocular pressure with advanced optic nerve cupping at 11 years of age. She was found to have a pigmented lesion overlying her iris and invading her angle. Trans-corneal fine needle aspirate biopsy demonstrated malignant melanoma of the iris. The patient subsequently underwent Iodine-125 plaque brachytherapy for the tumor. CONCLUSIONSand Importance: Early identification and treatment of iris melanoma may be associated with decreased risk of local progression and metastatic disease. Treatment of glaucoma in conjunction with uveal melanoma is complicated by tumor specific considerations, including treatment of the tumor and prevention of metastasis.
doi_str_mv 10.1016/j.ajoc.2018.05.009
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OBSERVATIONSA Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly elevated intraocular pressure with advanced optic nerve cupping at 11 years of age. She was found to have a pigmented lesion overlying her iris and invading her angle. Trans-corneal fine needle aspirate biopsy demonstrated malignant melanoma of the iris. The patient subsequently underwent Iodine-125 plaque brachytherapy for the tumor. CONCLUSIONSand Importance: Early identification and treatment of iris melanoma may be associated with decreased risk of local progression and metastatic disease. 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OBSERVATIONSA Caucasian female presented with left pupillary abnormalities at age 7, progressive iris changes at age 9, and markedly elevated intraocular pressure with advanced optic nerve cupping at 11 years of age. She was found to have a pigmented lesion overlying her iris and invading her angle. Trans-corneal fine needle aspirate biopsy demonstrated malignant melanoma of the iris. The patient subsequently underwent Iodine-125 plaque brachytherapy for the tumor. CONCLUSIONSand Importance: Early identification and treatment of iris melanoma may be associated with decreased risk of local progression and metastatic disease. Treatment of glaucoma in conjunction with uveal melanoma is complicated by tumor specific considerations, including treatment of the tumor and prevention of metastasis.</abstract><doi>10.1016/j.ajoc.2018.05.009</doi></addata></record>
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title Iris melanoma presenting as childhood glaucoma
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