Unmyelinated primary afferents from adjacent spinal nerves intermingle in the spinal dorsal horn: A possible mechanism contributing to neuropathic pain

Abstract Peripheral nerve injury in animals can cause neuropathic pain often expressed in the form of hyperalgesia and allodynia. Spinal nerve ligation, in which the fifth and sixth lumbar (L5 and L6) or only the L5 spinal nerve is ligated and cut, is a model commonly used to produce neuropathic pai...

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