Effects of pinealectomy and the treatment with melatonin on the temporal lobe epilepsy in rats

The aim of the present work was to analyze the effects of pinealectomy in the development of the epilepsy model induced by pilocarpine in adult male rats. Group I: Wistar male adult rats were submitted to pinealectomy, and 7 days after surgery, these animals received pilocarpine (350 mg/kg, i.p.) to...

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Veröffentlicht in:	Brain research 2005-05, Vol.1043 (1), p.24-31
Hauptverfasser:	de Lima, Eliângela, Soares, José Maria, del Carmen Sanabria Garrido, Yaima, Gomes Valente, Sandra, Priel, Margareth Rose, Chada Baracat, Edmund, Abrão Cavalheiro, Esper, da Graça Naffah-Mazzacoratti, Maria, Amado, Débora
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsants - pharmacology Apoptosis - drug effects Biological and medical sciences Denervation Disease Models, Animal Epilepsy Epilepsy, Temporal Lobe - chemically induced Epilepsy, Temporal Lobe - drug therapy Epilepsy, Temporal Lobe - physiopathology Experimental model Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampus - pathology Male Medical sciences Melatonin Melatonin - pharmacology Muscarinic Agonists Nervous system (semeiology, syndromes) Neurology Pilocarpine Pineal Gland - physiology Pineal Gland - surgery Pinealectomy Rats Rats, Wistar Status Epilepticus - chemically induced Status Epilepticus - drug therapy Status Epilepticus - physiopathology
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